Results 81 to 90 of about 1,069,681 (314)
A theory for investment across defences triggered at different stages of a predator-prey encounter [PDF]
, 2019 We introduce a general theoretical description of a combination of defences acting sequentially at different stages in the predatory sequence in order to make predictions about how animal prey should best allocate investment across different defensive ...
Broom, M. +4 more
core +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Prickly Defenders: A Review of Venomous Sea Urchins (Echinoidea)
Marine DrugsSea urchins, Echinoidea, are widely known for their defensive spines and pedicellariae, with some species having co-evolved venom in conjunction with those appendages. Despite this, their venomous arsenal remains poorly understood.
Sina Ehlert-Flaskämper +2 more
doaj +1 more source
Crying poor? The affordability of defence expenditure [PDF]
The May budget saw deep cuts made to Australia\u27s defence budget over the next few years. It will be up to next year\u27s Defence White Paper to decide what happens after that.
Mark Thomson
core
The CIA on Canadian Defence Policy [PDF]
, 2020 At the request of the Pentagon, in the spring of 1985 the Central Intelligence Agency prepared an assessment of Canadian defence policy. Brian Mulroney’s Progressive Conservatives had formed the government in the election of 4 September 1984 and, in the ...
Granatstein, J.L.
core +1 more source
Grasses and the resource availability hypothesis: the importance of silica-based defences [PDF]
, 2007 The resource availability hypothesis (RAH) predicts that allocation of resources to anti-herbivore defences differs between species according to their growth rate.
Ennos, Roland A. +2 more
core +2 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
The bacterial effector HopZ1a acetylates ZIP1 kinase to suppress Arabidopsis defence responses [PDF]
, 2018 During the plant-pathogen interaction, disease or resistance are determined in the plant by a series of molecular events. The plant detects Pathogen-Associated Molecular Patterns (PAMPs), such as flagellin, triggering a defence response called PTI (PAMP ...
Beuzon-Lopez, Carmen del Rosario +4 more
core
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Military Expenditures and Economic Growth in Pakistan [PDF]
This paper explores the impacts of defence expenditures on economic growth and other major economic variables in the Pakistan economy over the period 1972-1995. The results of Granger-causality tests show that there is bi-directional feedback between the
Akhtar Mahmood, Nasir M. Khilji
core