Results 41 to 50 of about 393,145 (302)

Ranking Support for the Strategic Development of Leading Universities: Lessons from the University Revolution in China

Університети і лідерство
The article uses the example of China to justify that the use of ranking tools contributes to the effective strategic development of leading universities.
Volodymyr Lugovyi, Olena Slyusarenko, Zhanneta Talanova   +2 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The economic dimension of US military assistance: security packages and their impact on Ukraine’s defense capability and financial sustainability

Економіка, управління та адміністрування
The article examines the economic dimension of US military assistance aimed at supporting Ukraine’s defense capabilities and stabilizing its financial system in the context of ongoing military aggression.
Yu.Yu. Moroz, A.A. Havrysh
doaj   +1 more source

Air Defense Efficiency Analysis of “Detecting, Guiding, Interfering and Damaging” Multi-Functional Directed Energy Weapons [PDF]

Hangkong bingqi
As directed energy weapons are neither well-integrated nor maximizing their effectiveness in the modern defense system, this paper proposes the multi-functional application of directed energy weapons for“detecting, guiding, interfering and damaging ...
Wu Taotao, He Miao, Xia Liangbin, Wang Qian, A Jingye
doaj   +1 more source

Cost calculation model for operational capabilities at the multinational operations execution stage [PDF]

Војно дело, 2014
The paper presents a model of operational capabilities cost calculation at the stage of operation execution, using example of the operational capabilities of forces in multinational operations, which can help calculate the financial resources required ...
Kovač Mitar, Stojković Dejan, Mitić Vlada   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The Growing Threat of Agroterrorism and Strategies for Agricultural Defense [PDF]

, 2020
Due to the dynamic nature of human conflict, non-traditional terror tactics have evolved to undermine the socioeconomic stability of targeted societies.
Forrest, Alyssa
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Research on Lightweight Dynamic Security Protocol for Intelligent In-Vehicle CAN Bus

Sensors
With the integration of an increasing number of outward-facing components in intelligent and connected vehicles, the open controller area network (CAN) bus environment faces increasingly severe security threats. However, existing security measures remain
Yuanhao Wang, Yinan Xu, Zhiquan Liu, Suya Liu, Yujing Wu   +4 more
doaj   +1 more source

PERSPECTIVES ON INTEROPERABILITY INTEGRATION WITHIN NATO DEFENSE PLANNING PROCESS [PDF]

Journal of Defense Resources Management, 2011
Interoperability is not a new area of effort at NATO level. In fact, interoperability and more specifi cally standardization, has been a key element of the Alliance’s approach to fi elding forces for decades.
Florian CIOCAN
doaj