Results 51 to 60 of about 393,145 (302)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Eve of Global Conflict or Contra Spem Spero?
Сравнительная политикаThe article contains the description of the world political context that influences the evolution of the military-political sphere. The articles of the presented issue are devoted to this analysis. As a methodological framework, it is proposed to use the
O. V. Gaman-Golutvina
doaj +1 more source
Autonomous weapon systems and international humanitarian law: a reply to the critics [PDF]
, 2013 In November 2012, Human Rights Watch, in collaboration with the International Human Rights Clinic at Harvard Law School, released Losing Humanity: The Case against Killer Robots.[2] Human Rights Watch is among the most sophisticated of human rights ...
Schmitt, Michael
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Assessing National and Military Security of Russia: Established Procedure and How to Improve It
Вестник Московского Университета. Серия XXV: Международные отношения и мировая политика, 2020 This paper examines established procedure of assessing national and military security of the Russian Federation and outlines ways how to improve it. The author unveils deficiencies of the current set of indicators for measuring national and military ...
S. P. Belokon’
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Norsk forsvarssamarbeid med Nederland og Sverige. Ikke så like likevel? [PDF]
, 2010 The security environment after the Cold War has created new challenges but also new opportunities. With no Iron Curtain dividing Europe, new patterns of cooperation in the field of defense and security have emerged.
Henriksen, Kjetil
core
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
Power System Attack-Defense Collaborative Model Based on Self-Attention and Multi-Modal Fusion [PDF]
Dianli jianshe[Objective] Aiming at the problems of adversarial attack risks and insufficient offensive-defense coordination of data-driven algorithms in new power systems， a theoretical framework for co-optimization of adversarial attacks and defense is established ...
WU Runze, ZHANG Puyang, GUO Haobo, WANG Jiarong
doaj +1 more source