Results 31 to 40 of about 408,353 (261)

Types and historical roles of secret gates: a new understanding of the Ming Great Wall based on a digital heritage survey

Journal of Asian Architecture and Building Engineering, 2023
The database of images of the Ming Great Wall, along with on-site investigation and verification, has allowed more than 120 secret gate sites to be located and classified for the first time.
Zhe Li, Xiaolong Tuo, Mengdi Zhang
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis

iScience
Summary: AMBRA1, which was initially reported to be essential for nervous system development via autophagy and cell proliferation control, also functions as a tumor suppressor by regulating the ubiquitination of D-type cyclins through interaction with ...
Hisako Akatsuka, Tomohiro Kashikawa, Kaori Masuhara, Mizuki Tokusanai, Chenyang Li, Yumi Iida, Chisa Okada-Yamaguchi, Yoshinori Okada, Masayuki Tanaka, Takahiro Suzuki, Norio Yamamoto, Katsuto Hozumi, Tomoaki Tanaka, Hirofumi Nakaoka, Kazuyoshi Hosomichi, Yu Hamaguchi, Michiaki Hamada, Yoshiki Shiraishi, Akihide Kamiya, Yoshihiko Nakamura, Kaito Harada, Abd Aziz Ibrahim, Takashi Yahata, Masato Ohtsuka, Naoya Nakamura, Hiroyuki Hosokawa, Minoru Kimura, Ituro Inoue, Takehito Sato   +28 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

HOSSP: Multimodal Remote Sensing Image Matching Using Symmetrically-Weighted Steerable Phase Orientation Histograms

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Robust and efficient multimodal image matching is essential for multisource data fusion in aerospace applications. However, existing methods often suffer from insufficient correct matches, large matching errors, and limited efficiency when spatial ...
Yue Zhang, Di Wu, Jianyuan Wang, Jinbao Chen, Ye Huang, Donghao Shi, Lixiao Deng, Jian Wang   +7 more
doaj   +1 more source

An investigation of the effectiveness of written emotional disclosure on defense mechanisms of alexithymic individuals [PDF]

Faṣlnāmah-i Farhang Mushavirah va Ravān/Darmānī, 2017
The aim of the present study was to investigate the effects of written emotional disclosure on the defense mechanisms of alexithymic people. A qausi-experimental pretest-posttest control group design was used to determine the effectiveness of written ...
Mohammad Ali Besharat, Elahe HAfezi, Ali Moghadam Zadeh   +2 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Personality Traits and Defense Mechanisms of Delinquent Boys in Correction and Rehabilitation Centers According to Types of Crime [PDF]

Ravānshināsī-i Afrād-i Istis̠nāyī, 2016
The aim of this study was comparing personality traits and defense mechanisms of delinquent boys in six categories of thievery, quarrel, drugs, murder, sexual abuse and abduction.
shamin sadri, Shahla Pezeshk, Ma'soomeh Tayebli   +2 more
doaj   +1 more source

The Reversible Methylation of m6A Is Involved in Plant Virus Infection

Biology, 2022
In recent years, m6A RNA methylation has attracted broad interest and is becoming a hot research topic. It has been demonstrated that there is a strong association between m6A and viral infection in the human system.
Jianying Yue, Yao Wei, Mingmin Zhao
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source