Objective The clusters of participants with a homogeneous psychological make-up can be identified using sophisticated machine learning techniques such as the two-step clustering algorithm.
Ahmed Waqas +4 more
doaj +1 more source
The dendritic cell niche in chronic obstructive pulmonary disease. [PDF]
The pulmonary innate immune system is heavily implicated in the perpetual airway inflammation and impaired host defense characterizing Chronic Obstructive Pulmonary Disease (COPD).
Haczku, Angela
core +3 more sources
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
Defense mechanisms in psychological health and sport success of athletes [PDF]
Introduction: Defense mechanisms represent a crucial component of our capacity to maintain emotional homeostasis. The present study is carried out with the purpose of determining the predictability of psychological health and sport success by defense ...
Afrooz Mousavi +2 more
doaj
Pricing and Investments in Internet Security: A Cyber-Insurance Perspective [PDF]
Internet users such as individuals and organizations are subject to different types of epidemic risks such as worms, viruses, spams, and botnets. To reduce the probability of risk, an Internet user generally invests in traditional security mechanisms ...
Golubchik, Leana, Pal, Ranjan
core
The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh +2 more
wiley +1 more source
Mechanisms by which antibiotics increase the incidence and severity of candidiasis and alter the immunological defenses [PDF]
Mildred S. Seelig
openalex +2 more sources
A Neural Model of How The Brain Represents and Compares Numbers [PDF]
Many psychophysical experiments have shown that the representation of numbers and numerical quantities in humans and animals is related to number magnitude.
Grossberg, Stephen, Repin, Dmitry
core +1 more source
Gastroduodenal mucosal defense mechanisms [PDF]
To highlight recent developments in the field of gastroduodenal mucosal defense with emphasis on lumen-gut interactions.There has been a growing interest in the physiological functions of luminal chemosensors present from tongue to colon that detect organic molecules in the luminal content associated with nutrient ingestion, usually associated with ...
Said, Hyder +2 more
openaire +4 more sources
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma +10 more
wiley +1 more source

