Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng +9 more
wiley +1 more source
<i>Arion vulgaris</i> pedal epithelium displays fluorescence patterns consistent with uptake of <i>Nicotiana tabacum</i> extracellular dye-labeled vesicles <i>ex vivo</i>. [PDF]
Liegertová M +4 more
europepmc +1 more source
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao +13 more
wiley +1 more source
The Impact of Abusive Supervision on Nurses' Organizational Silence: The Multiple Linear Mediation of Psychological Capital and Fear. [PDF]
Liang Y +4 more
europepmc +1 more source
Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du +5 more
wiley +1 more source
Continuing the Conversation for a Clinical Conceptualization of Attachment Trauma. [PDF]
Schimmenti A, Farina B.
europepmc +1 more source
TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang +14 more
wiley +1 more source
The importance of early primary relationships in the development and psychoanalytic understanding of emptiness: connecting developmental theory with practice. [PDF]
Papadopoulos D.
europepmc +1 more source

