Results 141 to 150 of about 13,449 (262)

Targeted Anti‐IL‐1 Immunomodulatory Therapy in Pediatric Onset PPP1R13L‐Related Arrhythmogenic Cardiomyopathy

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1807-1813, August 2026.
ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg   +9 more
wiley   +1 more source

External validation of the BAN‐ADHF diuretic‐resistance score in the DAPA‐RESIST clinical trial

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2960-2965, August 2026.
Diuretic resistance in worsening heart failure (HF) is associated with poorer outcomes and, although common, can be challenging to identify. The recently developed BAN‐ADHF score can potentially identify patients with worsening HF at risk of diuretic resistance.
Dominic M. Alfonso   +10 more
wiley   +1 more source

A Contemporary Review of Subcutaneous and Extravascular Implantable Cardiac Defibrillators. [PDF]

open access: yesJ Innov Card Rhythm Manag
Jalil A   +5 more
europepmc   +1 more source

Clinical and Echocardiographic Outcomes After Implantation of the ALLEGRA Transcatheter Valve Using the Fully Repositionable IMPERIA Delivery System: One‐Year Results of the EMPIRE I Study

open access: yesCatheterization and Cardiovascular Interventions, Volume 108, Issue 2, Page 540-547, August 1, 2026.
ABSTRACT Background The EMPIRE I study assessed the early (30 days) safety and efficacy of a new fully repositionable delivery system (IMPERIA) for the commercially available ALLEGRA transcatheter aortic valve in patients with either severe native aortic stenosis or a degenerated surgical bioprosthesis.
José Antonio Baz   +15 more
wiley   +1 more source

Unveiling New Insights: Reinterpreting DES Mutation, p.Arg383His, Through a Study of an Iranian Family With Isolated Hypertrophic Cardiomyopathy, Implication for Phenotype–Genotype Correlation Analysis

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Desmin, a crucial intermediate filament in muscle cells, maintains structural integrity in cardiac muscle and provides stability to striated muscle cells. Mutations in the DES gene lead to desminopathies, causing diverse cardiac and skeletal myopathies.
Saeideh Kavousi   +5 more
wiley   +1 more source

A Challenging Case of Advanced Cardiac Sarcoidosis Refractory to Infliximab Therapy

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Cardiac sarcoidosis can be life‐threatening, and lack of response to immunosuppressive therapy remains a significant challenge in active disease. We present a case of refractory cardiac sarcoidosis despite third‐line immunosuppression (infliximab). Ongoing multimodality assessment is essential for managing refractory cardiac sarcoidosis.
Manal Ibrahim   +4 more
wiley   +1 more source

Impella‐Assisted High‐Risk Percutaneous Coronary Intervention in Cardiogenic Shock With Low‐Flow, Low‐Gradient Aortic Stenosis and Multivessel Coronary Artery Disease: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Patients with cardiogenic shock, low‐flow, low‐gradient aortic stenosis, and multivessel coronary artery disease who are ineligible for surgery present a major therapeutic challenge. Percutaneous mechanical circulatory support may facilitate revascularization in this high‐risk population. A 69‐year‐old man presented after a mechanical fall and
Douni Roger   +3 more
wiley   +1 more source

A Case Report of Short‐Coupled Ventricular Fibrillation Unmasked During Post‐Infarction Inflammatory Remodeling

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT This case illustrates the rare clinical emergence of the short‐coupled ventricular fibrillation (SC‐VF) phenotype during the subacute remodeling phase following acute myocardial infarction (AMI). Although SC‐VF is traditionally characterized as an idiopathic syndrome occurring in structurally normal hearts, we report the case of a 49‐year‐old ...
ZiYu Zhao, Ming Ni, Bo Li, Songhua Li
wiley   +1 more source

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