Results 91 to 100 of about 2,668,670 (306)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Hepatocyte senescence and persistent liver injury in Fanconi anemia
Not available.
Jane Koo +8 more
doaj +1 more source
The Deficiency-One Theorem states that there exists a unique positive steady state in each positive stoichiometric class for weakly reversible deficiency-one mass action systems with one linkage class (regardless of the values of the rate coefficients ...
Boros, Balázs
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Lipid dysregulation after hematopoietic stem cell transplant
Transplant-associated thrombotic microangiopathy (TA-TMA) is a serious complication of allogeneic hematopoietic stem cell transplantation, primarily driven by endothelial injury and complement activation. Statins, combined with other drugs, are commonly
Jane Koo +13 more
doaj +1 more source
A review paper on Integrated Aquaculture Benefits Project at Federal College of Forestry, Ibadan [PDF]
This paper highlights some of the practices involved in integrated aquaculture such as poultry-cum-fish, pig-cum-fish, sheep and goat-cum-fish and grasscutter-cum-fish. Also the role of fisheries in alleviating protein deficiency was reviewed. Successful
Meduna, A.J., Samuel, A.A.
core
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

