Results 91 to 100 of about 1,030,121 (356)

Experimental ochratoxicosis A in Nile tilapia and its amelioration by some feed additives

International Journal of Veterinary Science and Medicine, 2018
Ochratoxin A (OTA) formation prevention is not usually available so counteracting strategies are urgent. This study investigated the toxic effects of OTA on Nile tilapia with trials to neutralize these effects by using some feed additives.
Amany M. Diab, Salem R.M., El-Keredy M.S. Abeer, Gehan I.E. Ali, Nagwan El-Habashi   +4 more
doaj  

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Changes of methylation at enhancers appear to be essential for HIV infection progression

Clinical Epigenetics
Background We studied the influence of the European HIV-1 subtype B (most common in the Western and Central Europe) and subtype A6 (prevalent in Eastern Europe including Ukraine and Russia) on host methylome during infection progression and in virus ...
Olga Taryma-Leśniak, Jan Bińkowski, Kaja Mielczak, Bogusz Aksak-Wąs, Malwina Karasińska-Cieślak, Marta Sobalska-Kwapis, Dominik Strapagiel, Miłosz Parczewski, Tomasz Kazimierz Wojdacz   +8 more
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. [PDF]

, 2010
ObjectiveThe islet in type 2 diabetes is characterized by β-cell apoptosis, β-cell endoplasmic reticulum stress, and islet amyloid deposits derived from islet amyloid polypeptide (IAPP).
Butler, Alexandra E, Butler, Peter C, Costes, Safia, Daval, Marie, Gurlo, Tatyana, Huang, Chang-jiang, Matveyenko, Aleksey V, Rizza, Robert A   +7 more
core   +2 more sources

Azolla pinnata mitigates pendimethalin induced immunotoxicity, oxidative stress and histopathological changes in Oreochromis niloticus

Scientific Reports
Aquatic animals face multiple threats, including pesticides, heavy metals, and other environmental pollutants, risking their health and survival. Limited bioremediation studies have been conducted on the detrimental impacts of herbicides on fish.
Nagwa I. S. Abu-Zahra, Mofeed Gouda, Mohamed M. Elseify, Mona E. Abass, Mohammed S. El-Gohary, Eman T. El-sokary   +5 more
doaj   +1 more source

Antiretroviral Therapy – Changes of Basic Laboratory Parameters in Hiv-Infected Bulgarian Patients

Acta Medica Bulgarica, 2015
HIV-1 infection keeps on being a global problem because of its pandemic character and the impossibility for eradication. The combined antiretroviral therapy (АRТ) remains the only treatment which has proven its effectiveness for maintaining the life of ...
Stojanova Yancheva Nina
doaj   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Factors Associated with Prenatal Folic Acid and Iron Supplementation Among 21,889 Pregnant women in Northern Tanzania: A Cross-Sectional Hospital-Based Study. [PDF]

, 2012
Folate and iron deficiency during pregnancy are risk factors for anaemia, preterm delivery, and low birth weight, and may contribute to poor neonatal health and increased maternal mortality.
Daltveit, Anne Kjersti, Hoyo, Cathrine, Lie, Rolv Terje, Manongi, Rachael, Ogundipe, Olukemi, Oneko, Olola, Østbye, Truls   +6 more
core   +4 more sources

[Prevention of iodine deficiency diseases: focus on regional targeted programs]. [PDF]

Probl Endokrinol (Mosk), 2022
Dedov II, Platonova NM, Troshina EA, Makolina NP, Belovalova IM, Senyushkina ES, Melnichenko GA.   +6 more
europepmc   +1 more source