Results 101 to 110 of about 1,194,112 (311)

Azolla pinnata mitigates pendimethalin induced immunotoxicity, oxidative stress and histopathological changes in Oreochromis niloticus

Scientific Reports
Aquatic animals face multiple threats, including pesticides, heavy metals, and other environmental pollutants, risking their health and survival. Limited bioremediation studies have been conducted on the detrimental impacts of herbicides on fish.
Nagwa I. S. Abu-Zahra, Mofeed Gouda, Mohamed M. Elseify, Mona E. Abass, Mohammed S. El-Gohary, Eman T. El-sokary   +5 more
doaj   +1 more source

[Regional target program «Prevention of iodine deficiency diseases for 202X-202X»]. [PDF]

Probl Endokrinol (Mosk), 2022
Troshina EA, Platonova NM, Makolina NP, Belovalova IM, Senyushkina ES, Melnichenko GA, Dedov II.   +6 more
europepmc   +1 more source

Food is our medicine [PDF]

, 2012
The paper describes the role of foods and nutrition in the promotion of human health. The relationship between foods, metabolism, homeostasis and metabolic disorder are briefly described.
Sarmidi, Mohamad Roji
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Outcomes with third-party virus-specific T cells after the use of single-antigen cell lines to predict HLA restriction

Blood Advances
: Patients with significant T-cell dysfunction from chemotherapy or hematopoietic stem cell transplant are at significant risk for complications of viral infections.
Jeremy D. Rubinstein, Giang Pham, Anusha Sridharan, Ruby Khoury, YunZu M. Wang, Zahra Hudda, Jamie Wilhelm, Daniel A. Lichtenstein, Daria Heyenbruch, Jose A. Cancelas, Stella M. Davies, Carolyn Lutzko, Michael S. Grimley   +12 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Antiretroviral Therapy – Changes of Basic Laboratory Parameters in Hiv-Infected Bulgarian Patients

Acta Medica Bulgarica, 2015
HIV-1 infection keeps on being a global problem because of its pandemic character and the impossibility for eradication. The combined antiretroviral therapy (АRТ) remains the only treatment which has proven its effectiveness for maintaining the life of ...
Stojanova Yancheva Nina
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source