Results 211 to 220 of about 1,030,121 (356)

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Micronutrient status of patients with diabetic foot: A systematic review. [PDF]

Asia Pac J Clin Nutr
Batarbekova S, Zhunussova D, Derbissalina G, Bekbergenova Z, Maksimova N, Umbetzhanova A, Kelimberdiyeva E, Kassymova R, Kuanyshbayeva G, Imangaliyeva A.   +9 more
europepmc   +1 more source

α-1-Antitrypsin Deficiency in Liver Disease: The Extent of the Problem

, 1976
Rosemarie Lucianin Fisher, Lesley Taylor, Sheila Sherlock   +2 more
openalex   +1 more source

GEORGE BUDD (1808–1882) AND NUTRITIONAL DEFICIENCY DISEASES [PDF]

, 1973
R. E. Hughes
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Iron Deficiency and Iron Deficiency Anemia in Chronic Disease-Common, Important, and Treatable. [PDF]

J Clin Med
Moum B, Lindgren S.
europepmc   +1 more source

A profound deficiency of (CH3-14C) choline sphingomyelin-cleaving enzyme in niemann-pick disease type B.

, 1975
Tadao Orii, Fukumi Nakamura, Tooru Kudoh, Keiko Tsuchihashi, Tooru Nakao   +4 more
openalex   +2 more sources

Granulopoietic and erythropoietic activity in patients with anemias of iron deficiency and chronic disease [PDF]

, 1977
T Mahmood, William A. Robinson, JE Kurnick, R Vautrin   +3 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Paracentral acute middle maculopathy as a major clinical manifestation of adenosine deaminase-2 deficiency. [PDF]

BMC Ophthalmol
Ariello LE, de Souza Andrade T, Fernandes RD, Cunha LP, Monteiro MLR.   +4 more
europepmc   +1 more source