Results 61 to 70 of about 1,179,077 (360)
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Mature Incisor With Internal Resorption: Laser-Assisted Regenerative Endodontic Procedures
International Dental JournalIntroduction: Internal root resorption (IRR), characterized by progressive dentin destruction, may cause root perforations, fracture, and even tooth loss. Regenerative endodontic procedures (REPs), which can promote root development, lack strong evidence
Ruonan Chen, Guoying Lu, Xiuqing Wang
doaj +1 more source
Evaluation of Glycated Albumin (GA) and GA/Hba1c Ratio for Diagnosis of Diabetes and Glycemic Control: A Comprehensive Review [PDF]
, 2017 Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and ...
Abdolrahim, Mojgan +6 more
core +3 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia
Nature Communications, 2020 The alternative splicing regulator MBNL1 is overexpressed in MLL-rearranged leukaemia. Here, the authors show that MBNL1-mediated alternative splicing leads to a specific splicing profile in MLL-rearranged leukaemia and loss or inhibition of MBNL1 ...
Svetlana S. Itskovich +11 more
doaj +1 more source
Haematologica, 2021 Although great advances have been made in understanding the pathobiology of mixed lineage leukemia-rearranged (MLL-r) leukemias, therapies for this leukemia have remained limited, and clinical outcomes remain bleak.
Gabriel Gracia-Maldonado +10 more
doaj +1 more source
Fortification and health: challenges and opportunities. [PDF]
, 2015 Fortification is the process of adding nutrients or non-nutrient bioactive components to edible products (e.g., food, food constituents, or supplements). Fortification can be used to correct or prevent widespread nutrient intake shortfalls and associated
Bailey, Regan L +11 more
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Mitochondrial Dysfunction in Aging and Diseases of Aging. [PDF]
, 2019 Mitochondria have been increasingly recognized as the important players in the aging process [...]
Haas, Richard H
core +2 more sources
The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells
FEBS Letters, EarlyView.The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman +3 more
wiley +1 more source
Soil, grain and water chemistry and human selenium imbalances in Enshi district, Hubei Province, China [PDF]
, 1996 Many elements which are essential to human and other animal health in small doses can be toxic if ingested in excess. Selenium (Se), a naturally occurring metalloid element is found in all natural materials on earth including rocks, soils, waters, air,
Fordyce, F.M. +3 more
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