Results 111 to 120 of about 7,903,433 (276)
Beyond the Surface: A Consensual Qualitative Research into the Multifaceted Nature of Bullying
Behavioral SciencesBullying is a significant social issue, yet research often relies on quantitative methods. Our study aimed to gain a deeper insight by giving students a voice in expressing their experiences and perceptions, focusing on how youth define and perceive ...
Laura Menabò +4 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Application progress of knowledge translation theory in clinical practice
Huli yanjiu, 2018 This article reviewed the definition,classification,theory frame,and the application status quo in the clinical practice of knowledge translation,aimed at encouraging nursing staff in China to translate evidence based knowledge into clinical practice,and
王慧 +4 more
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Related concepts and the development of clinical research nurse
Huli yanjiu, 2018 This article reviewed the definition and practice scope of clinical research nursing in China and abroad;definition and role function of clinical research nurse (CRN);further analyzed the relation and distinction among CRN,advanced practice nurse(ANP ...
季梦婷, 杨艳
doaj
Digital Organizational Culture: Concept and Scale Development
Journal the WinnersThe research presented a multifaceted conceptualization of digital organizational culture (DOC) to address challenges from a divergent understanding of critical concept among strategic decision-makers.
Daniel Lukito +3 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Online Course: Definition and Classification
Высшее образование в России, 2018 Online course study is relevant due to their active integration into higher education in Russia and the variety of ways they can be used to implement the concept of life-long education.
N. V. Grechushkina
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source