Results 201 to 210 of about 364,159 (261)

Reinterpreting I² Thresholds: Toward Context-Specific Heterogeneity Assessment in Evidence Synthesis. [PDF]

Cochrane Evid Synth Methods
Martí-Carvajal AJ, Streiner DL.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

The International Glossary on Infertility and Fertility Care, 2025†. [PDF]

Hum Reprod
Zegers-Hochschild F, Dyer S, Adamson GD, Baker V, Barnhart K, Bhattacharya S, Boothroyd C, Chambers G, De Mouzon J, Elgindy E, Fauser B, Hammarberg K, Horton M, Ishihara O, Jwa SC, Khrouf M, Kupka M, Lamb DJ, Luna M, Martinez AG, Monseur B, Nagy P, Pinborg A, Racowsky C, Rienzi L, Schlegel P, Schmidt L, Vuong LN, Turner T, Vázquez-Levin MH, Wada I, Wells D, Wyns C.   +32 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

A simple model captures key characteristics of biological non-deterministic genotype-phenotype maps. [PDF]

PLoS Comput Biol
Martin NS.
europepmc   +1 more source

Toward precision for bronchopulmonary dysplasia: Moving past current definitions. [PDF]

J Perinatol
Kielt MJ, Nelin TD, Abman SH, Nelin LD.
europepmc   +1 more source

CICU Workforce Surveys: Interpret With Caution. [PDF]

JACC Adv
Lotfi A.
europepmc   +1 more source

Defining the Vascular Anomalies in Maffucci Syndrome: A Systematic Review. [PDF]

Plast Reconstr Surg Glob Open
Fang E, Zhou T, Haas J, Yuen K, Choi M.
europepmc   +1 more source