Results 101 to 110 of about 5,695,375 (162)

Cryo‐EM structure of GH43 β‐Xylosidase from Enterobacter cloacae provides insights into substrate specificity and the role of an auxiliary domain in enzymatic activity

The FEBS Journal, EarlyView.
Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti, Andre Schutzer Godoy, Caio Cesar Mello Capetti, Rafaela Sachetto Fernandes, Vanessa O. A. Pellegrini, Ornella M. Ontañon, Eleonora Campos, Rodrigo V. Portugal, Igor Polikarpov   +8 more
wiley   +1 more source

A Bayesian approach to spectroscopic depth sectioning for locating dopant atoms

Journal of Microscopy, EarlyView.
Abstract Locating dopants in 3D is of great interest as advanced materials and devices increasingly rely on control at atomic dimensions, and microscopy tools are constantly in development for this purpose. One potential tool is electron energy loss spectroscopy (EELS) depth sectioning, where a core‐loss signal is collected as a function of electron ...
Michael Deimetry, Timothy C. Petersen, Matthew Weyland, Scott D. Findlay   +3 more
wiley   +1 more source

The Role of Spectacle Lenses in the Control and Management of Myopia Progression: A Narrative Review

Life
The number of people affected by myopia worldwide is estimated to reach two billion and to further grow. Therefore, numerous treatment approaches (pharmacological, behavioral, environmental, and optical) have been put forth to slow the progression of ...
Livio Vitiello, Filippo Lixi, Valerio Calabresi, Mario Troisi, Ilaria De Pascale, Alfonso Pellegrino, Giulia Coco, Aldo Vagge, Giuseppe Giannaccare   +8 more
doaj   +1 more source

CLDN18.2 in pancreatic ductal adenocarcinoma: Biomarker assessment, spatial heterogeneity and therapeutic modality selection

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review presents a framework for selecting Claudin 18.2 (CLDN18.2)‐directed treatment modalities in pancreatic ductal adenocarcinoma according to tumour antigen coverage and spatial distribution. Representative assessment at baseline and reassessment after progression can guide treatment adaptation over time.
Ruyu Tan, Zhexin Zhang, Jiaxin Wang, Roland Andersson, Daniel Ansari, Jinfei Chen   +5 more
wiley   +1 more source

Understanding higher‐order aberrations in keratoconus

Optometry and Vision Science, Volume 103, Issue 10, October 2026.
ABSTRACT Keratoconus is characterized by progressive thinning and increasing irregularity of the cornea, leading to substantial degradation in optical quality through the induction of both lower‐ and higher‐order aberrations (HOAs). In addition to inducing myopic and astigmatic refractive error, asymmetric corneal steepening generates complex optical ...
Gavin Swartz, Khyber Alam, Alex Gentle, Laura E. Downie   +3 more
wiley   +1 more source

The Lord of the Rings: Cysteine bonds crosslink the tail of siphovirus

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Long, non‐contractile tails composed of helical hexameric protein repeats that assemble into continuous tubular structures characterize siphoviruses. The siphovirus tail tube protein gp39 contains two cysteine residues per monomer. Cryo‐electron microscopy revealed that these cysteines are oriented toward the interface between the rings, which
Simona Povilonienė, Giedrius Sasnauskas, Giedrė Tamulaitienė, Greta Labutytė, Martynas Talaikis, Algirdas Mikšys, Aurelija Zajančkauskaitė, Lidija Truncaitė, Rolandas Meškys, Vida Časaitė   +9 more
wiley   +1 more source

The lower γ region supports forward rotation in the latter half of the 80° substep of F1‐ATPase

Protein Science, Volume 35, Issue 10, October 2026.
Abstract F1‐ATPase achieves unidirectional rotation of its γ shaft through coordinated conformational cycling of the α3β3 ring, yet how shaft–ring interactions contribute to the directionality of rotation remains unclear. Here we analyzed an axle‐less TF1, in which the lower γ region is truncated, by combining single‐molecule rotation assays with cryo ...
Tomo Uchiyama, Hiroshi Ueno, Meghna Sobti, Emily J. Furlong, Simon H. J. Brown, Alastair G. Stewart, Hiroyuki Noji   +6 more
wiley   +1 more source

Ultrasonic Vibration Assisted Laser Processing: A Hybrid Paradigm for Extreme Surface Enhancement

Rare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT Traditional laser processing techniques offer many advantages, but they often encounter limitations such as heat‐affected zones, recast layers, residual tensile stresses, and poor surface finish. The integration of ultrasonic vibration (UV) presents a promising hybrid approach to overcome these challenges by introducing beneficial effects like
Aziz Ul Hassan Mohsan, Xuedao Shu, Hu Zong, Su Zhao, Khamis Essa, Di Tie, Changyong Chen   +6 more
wiley   +1 more source

Astigmatism and maternal myopia as important factors affecting success rate of DIMS lens treatment

BMJ Open Ophthalmology
Objective To assess the efficacy of myopia control spectacle lenses (defocus incorporated multiple segments/DIMS) in slowing myopia progression among a diverse Central European paediatric population and investigate the contribution of baseline parameters
Christof Meigen, Adrienne Csutak, Patricia Domsa, Éva M Bankó, Judit Körtvélyes, Rita Széchey, Krisztina Lantos, Zoltán Zsolt Nagy   +7 more
doaj   +1 more source

Toledo Chapter of The Girlfriends, Incorporated scrapbook

This scrapbook was created by the Toledo Chapter of The Girlfriends, Incorporated. The scrapbook includes programs, invitations, photographs, newspaper clippings, and sheet music.
Toledo Chapter of The Girlfriends, Incorporated
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