Results 51 to 60 of about 24,619,547 (331)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Deformation and tension analysis during embryonic development [PDF]

, 2017
The aim of this document is to introduce the reader into the process, through microscopic threedimensional images, of the cellular embryonic deformation of the Drosphila Melanogaster fly through its development.
Brugarolas Roca, Alejandro
core  

Deformation analysis of matrix models

, 1994
The Tracy-Widom equations associated with level spacing distributions are realized as a special case of monodromy preserving deformations.Comment: 23 ...
Harnad, Its, Jimbo, Jimbo, Jimbo, Jimbo, John Palmer, Malgrange, Moore, Moore, Palmer, Tracy   +11 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Deformation analysis in the bank slopes in the reservoir area of Baihetan Hydropower Station based on SBAS-InSAR technology

Zhongguo dizhi zaihai yu fangzhi xuebao, 2022
The analysis of potential landslide deformation on the reservoir bank is an important link to ensure the safe operation of national water conservancy and hydropower facilities.
Zhengrong YANG, Wenfei XI, Zhengtao SHI, Bo XIAO, Dingyi ZHOU   +4 more
doaj   +1 more source

An advanced meshless technique for large deformation analysis of metal forming [PDF]

, 2008
The large deformation analysis is one of major challenges in numerical modelling and simulation of metal forming. Although the finite element method (FEM) is a well-established method for modeling nonlinear problems, it often encounters difficulties for ...
Gu, YuanTong, Yan, Cheng, Yarlagadda, Prasad   +2 more
core   +3 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A Comprehensive Review of Transformer Winding Diagnostics: Integrating Frequency Response Analysis with Machine Learning Approaches

Energies
Frequency Response Analysis (FRA) is a proven method for detecting mechanical faults in transformers, such as winding deformations and short circuits. However, traditional FRA interpretation relies heavily on visual and subjective comparison of frequency
Meysam Beheshti Asl, Issouf Fofana, Fethi Meghnefi, Youssouf Brahami, Joao Pedro Da Costa Souza   +4 more
doaj   +1 more source

Visualization of the Strain-Rate State of a Data Cloud: Analysis of the Temporal Change of an Urban Multivariate Description

Applied Sciences, 2019
One challenging problem is the representation of three-dimensional datasets that vary with time. These datasets can be thought of as a cloud of points that gradually deforms.
Lorena Salazar-Llano, Camilo Bayona-Roa
doaj   +1 more source

Frequency shifts in natural vibrations in pantographic metamaterials under biaxial tests [PDF]

, 2017
In this paper a 2D continuum model, thought as the homogenized limit of a microstructured pantographic sheet, is studied. The microstructure is characterized by two families of parallel fibers, whose deformation measures account for bending, elongation ...
Battista, Antonio, Del Vescovo, Dionisio, Rizzi, Nicola Luigi, Turco, Emilio   +3 more
core   +1 more source