Results 121 to 130 of about 32,140 (211)

Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo   +11 more
wiley   +1 more source

Path degeneracy and applications

open access: yesCoRR
In this work, we relate girth and path-degeneracy in classes with sub-exponential expansion, with explicit bounds for classes with polynomial expansion and proper minor-closed classes that are tight up to a constant factor (and tight up to second order terms if a classical conjecture on existence of $g$-cages is verified).
Yuquan Lin, Patrice Ossona de Mendez
openaire   +2 more sources

A computational model of view degeneracy

open access: yes, 1999
ÐWe quantify the observation by Kender and Freudenstein [24] that degenerate views occupy a significant fraction of the viewing sphere surrounding an object.
John K. Tsotsos   +2 more
core  

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell   +2 more
wiley   +1 more source

Unsupervised Machine Learning Identifies Shared Biomechanical and Clinical Variation in Individuals with Knee Osteoarthritis and High BMI: A Secondary Analysis of the IDEA Trial

open access: yesArthritis Care &Research, Accepted Article.
Objective High body mass index (BMI≥27 kg/m2) and aberrant gait biomechanics are primary risk factors for knee osteoarthritis (KOA), yet the specific loading patterns linked to clinical disease features remain unclear. Unsupervised machine learning (ML) was used to identify vertical ground reaction force (vGRF) waveform modes of variation and ...
Ashley N. Buck   +10 more
wiley   +1 more source

On “Relativistic Degeneracy.” [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1935
openaire   +2 more sources

Towards a theory of frustrated degeneracy

open access: yes, 2003
We study the question of how degeneracy of finite toroidal and 3-dimensional spin glasses depends on frustration. Using the transfer matrix method we obtain lower and upper bounds for maximum degeneracy in both 2-dimensional and 3-dimensional ...
Vondrák, Jan, Loebl, Martin
core   +1 more source

dynoGP: Deep Gaussian Processes for Dynamic System Identification

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This work introduces a novel class of deep models for system identification, dynamical deep Gaussian processes, which combine the strengths of data‐driven methods, such as those based on neural network architectures, with the ability to output a probability distribution for uncertainty representation.
Alessio Benavoli   +3 more
wiley   +1 more source

On degeneracy of dispersive waves at the bulk wave velocities

open access: yes, 2019
Degeneracy of the linear dispersion wave equation at the phase velocities coinciding with the bulk wave velocities is observed and analysed. Spectral analysis of Pochhammer – Chree equation is performed.
Sergey Kuznetsov, Alla Ilyashenko
core   +1 more source

Effects of Mg on Microstructure and Solidification of a Hypereutectic Zn–8 wt.%Al Alloy

open access: yesAdvanced Engineering Materials, EarlyView.
An appreciable set of results involving thermal data, microstructure, chemical composition, and microstructural growth laws is reported for ZnAlMg alloys. Such results demonstrate that ZnAlMg alloys have high potential for applications in automotive self‐lubricating components, batteries, and electrical systems.
Raí B. de Sousa   +6 more
wiley   +1 more source

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