Results 111 to 120 of about 146,108 (290)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Study on Hysteresis Model of Welding Material in Unstiffened Welded Joints of Steel Tubular Truss Structure

open access: yesApplied Sciences, 2018
The weld form of intersecting joints in a steel tubular truss structure changes with the various intersecting curves. As the key role of joints in energy dissipation and seismic resistance, the weld is easy to damage, as a result the constitutive ...
Yaqi Suo, Wenwei Yang, Peng Chen
doaj   +1 more source

Quantum Degenerate Systems

open access: yes, 2012
Degenerate dynamical systems are characterized by symplectic structures whose rank is not constant throughout phase space. Their phase spaces are divided into causally disconnected, nonoverlapping regions such that there are no classical orbits ...
Dirac P. A. M.   +5 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Quantum characteristics of a nondegenerate three-level laser with NDPA pumped by electron bombardment

open access: yesPhysics Open
This study investigates the entanglement and squeezing characteristics of light generated by a non-degenerate, three-level laser with a non-degenerate parametric amplifier, which is pumped by electron bombardment to the top level and coupled to a two ...
Aliyyi Adem
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Initial-value problems for linear distributed-order differential equations in Banach spaces

open access: yesElectronic Journal of Differential Equations, 2018
We solve the Cauchy problem for inhomogeneous distributed-order equations in a Banach space with a linear bounded operator in the right-hand side, with respect to the distributed Caputo derivative.
Vladimir E. Fedorov   +1 more
doaj  

Quantum spatial propagation of squeezed light in a degenerate parametric amplifier [PDF]

open access: yes
Differential equations which describe the steady state spatial evolution of nonclassical light are established using standard quantum field theoretic techniques.
Deutsch, Ivan H., Garrison, John C.
core   +1 more source

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