Results 101 to 110 of about 146,108 (290)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Growth processes related to the dispersionless Lax equations

, 2006
This paper is a short review of the connection between certain types of growth processes and the integrable systems theory, written from the viewpoint of the latter.
A. Zabrodin, Bensimon, Boyarsky, Chau, Date, Davis, Dubrovin, Gibbons, Gibbons, Gibbons, Hille, Kharchev, Kodama, Krichever, Krichever, Krichever, Lawler, Löwner, Manas, Manas, Marshakov, Mineev-Weinstein, Orlov, Richardson, Schramm, Takasaki, Takasaki, Takebe, Teodorescu, Ueno, Wiegmann, Yu, Zabrodin   +32 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Degenerate Neutron Capture Rates in the Threshold of Neutron Star–Black Hole Mergers

The Astrophysical Journal
We first show that the rate of energy generation due to neutron capture rates can be important in neutron star–black hole mergers (NS–BH mergers) by considering neutron degeneracy.
Rita K. Y. Lau
doaj   +1 more source

Principal Symbol of Euler-Lagrange Operators

, 2016
We shall introduce the principal symbol for Euler-Lagrange operators and use them to charac- terise well-posed initial value problems. We shall clarify how constraints can arise in Lagrangian covariant theories by extending the standard treatment in GR ...
Fatibene, Lorenzo, Garruto, Simon
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Evolution to a singular measure and two sums of Lyapunov exponents

, 2011
We consider dissipative dynamical systems represented by a smooth compressible flow in a finite domain. The density evolves according to the continuity (Liouville) equation.
Batchelor G K, Evans D J, Falkovich G, Falkovich G, Fouxon I, Gawedzki K, Itzhak Fouxon, Ma S-K, Oseledets V I, Sinai Ya G   +9 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Degenerate Sectors of the Ashtekar Gravity

, 1999
This work completes the task of solving locally the Einstein-Ashtekar equations for degenerate data. The two remaining degenerate sectors of the classical 3+1 dimensional theory are considered.
Ashtekar A, Bengtsson I, Bengtsson I, Bengtsson I, Jacek Wisniewski, Jacobson T, Jacobson T, Jerzy Lewandowski, Lewandowski J, Ma Y, Matschull H J   +10 more
core   +1 more source

Analytic semigroups and some degenerate evolution equations defined on domains with corners

Discrete and Continuous Dynamical Systems, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
ALBANESE, Angela Anna, MANGINO, Elisabetta Maria   +1 more
openaire   +3 more sources