Results 71 to 80 of about 145,745 (278)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Entropy solutions for nonlinear degenerate elliptic-parabolic-hyperbolic problems
Electronic Journal of Differential Equations, 2014 We consider the nonlinear degenerate elliptic-parabolic-hyperbolic equation $$ \partial_t g (u) - \Delta b (u) - \hbox{div} \Phi(u) = f (g (u) ) \quad \text{in } (0,T) \times \Omega, $$ where g and b are nondecreasing continuous functions, $\Phi$
Ning Su, Li Zhang
doaj
Some applications of the generalized Laplace transform and the representation of a solution to Sobolev-type evolution equations with the generalized Caputo derivative [PDF]
Bulletin of the Polish Academy of Sciences: Technical SciencesWe introduce the Sobolev-type multi-term μ-fractional evolution with generalized fractional orders with respect to another function. We make some applications of the generalized Laplace transform.
Mustafa Aydin, Nazim Mahmudov
doaj +1 more source
Evolution to a singular measure and two sums of Lyapunov exponents
, 2011 We consider dissipative dynamical systems represented by a smooth compressible flow in a finite domain. The density evolves according to the continuity (Liouville) equation.
Batchelor G K +9 more
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Network of interacting neurons with random synaptic weights [PDF]
ESAIM: Proceedings and Surveys, 2019 Since the pioneering works of Lapicque [17] and of Hodgkin and Huxley [16], several types of models have been addressed to describe the evolution in time of the potential of the membrane of a neuron.
Grazieschi Paolo +5 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Entropy, 2020 The approach based on the Wigner function is considered as a viable model of quantum transport which allows, in analogy with the semiclassical Boltzmann equation, to restore a description in the phase-space.
Vito Dario Camiola +2 more
doaj +1 more source
The Motion of closed hypersurfaces in the central force fields
, 2016 This paper studies the large time existence for the motion of closed hypersurfaces in a radially symmetric potential. In physical, this surface can be considered as an electrically charged membrane with a constant charge per area in a radially symmetric ...
Yan, Weiping
core +1 more source