Results 201 to 210 of about 894,956 (297)

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

Lovastatin-Loaded Nanoparticles in a Thermosensitive Chitosan Hydrogel as a Sustained Release System for Treating Intervertebral Disc Degeneration: In Vitro Cell Culture Study and In Vivo Evaluation Using a Needle-Puncture Induced Degeneration Model in Rat Caudal Discs. [PDF]

JOR Spine
Chen CW, Cheng YH, Yang KC, Huang CC, Hu MH, Sun YH, Wang JL, Yang SH.   +7 more
europepmc   +1 more source

6ER-004 Vision related quality of life in patients with diabetic macular oedema and age-related macular degeneration treated with anti-vascular growth factor therapy or dexamethasone [PDF]

Gabriel Mercadal-Orfila, P. Ventayol, J Serrano, Sergio Herrera   +3 more
openalex   +1 more source

Criteria for the diagnosis of corticobasal degeneration

Neurology, 2013
M. Armstrong, I. Litvan, A. Lang, T. Bak, K. Bhatia, B. Borroni, A. Boxer, D. Dickson, M. Grossman, M. Hallett, K. Josephs, A. Kertesz, Suzee E Lee, B. Miller, S. Reich, D. Riley, E. Tolosa, A. Tröster, M. Vidailhet, W. Weiner   +19 more
semanticscholar   +1 more source

Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis

Advanced Healthcare Materials, EarlyView.
Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim, Sung Sik Hur, Jae Hong Park, Myung Jin Ban, Jin‐Young Kim, Joo Hyun Kim, Ji Hyae Choo, Hae‐Won Kim, Ju Hun Lee, Man Ryul Lee, Yongsung Hwang   +10 more
wiley   +1 more source

Can Laser Retinopexy Prevent Retinal Detachment in Asymptomatic, High-Risk Eyes? [PDF]

Clin Ophthalmol
Morris RE, Sapp MR, Conn DR, Chawla H, Kuhn F.   +4 more
europepmc   +1 more source

Additional file 2: of Estimating cumulative pathway effects on risk for age-related macular degeneration using mixed linear models

, 2015
Jacob B. Hall, Jessica N. Cooke Bailey, Joshua Hoffman, Margaret A. Pericak‐Vance, William K. Scott, Jaclyn L. Kovach, Stephen G. Schwartz, Anita Agarwal, Milam A. Brantley, Jonathan L. Haines, William S. Bush   +10 more
openalex   +1 more source

Cell Calcification Models and Their Implications for Medicine and Biomaterial Research

Advanced Healthcare Materials, EarlyView.
Calcification, is the process by which the tissues containing minerals are formed, occurring during normal physiological processes, or in pathological conditions. Here, it is aimed to give a comprehensive overview of the range of cell models available, and the approaches taken by these models, highlighting when and how methodological divergences arise,
Luke Hunter, Caterina Vanelli Coralli, Robert Dzhanaev, Aaron Morgan, Willi Jahnen‐Dechent, Sergio Bertazzo   +5 more
wiley   +1 more source

Markedly Lower Rates of Age-Related Macular Degeneration in Malta Compared to European Countries: Results from The Malta Eye Study, Indicating Possible Divergent Genetic Ancestry? [PDF]

Clin Ophthalmol
Agius D, Mamo JJ, Calleja N, Cassar D, Marku X, Nappa MC, Zammit M, Pace ME, Carbonaro F.   +8 more
europepmc   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source