Results 61 to 70 of about 4,732,020 (409)

Automatic detection and counting of retina cell nuclei using deep learning [PDF]

open access: yesProceedings Volume 11317, Medical Imaging 2020: Biomedical Applications in Molecular, Structural, and Functional Imaging; 113172I (2020), 2020
The ability to automatically detect, classify, calculate the size, number, and grade of retinal cells and other biological objects is critically important in eye disease like age-related macular degeneration (AMD). In this paper, we developed an automated tool based on deep learning technique and Mask R-CNN model to analyze large datasets of ...
arxiv   +1 more source

Desktop-Stereolithography 3D Printing of a Polyporous Extracellular Matrix Bioink for Bone Defect Regeneration

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
IntroductionDecellularized tendon extracellular matrix (tECM) perfectly provides the natural environment and holds great potential for bone regeneration in Bone tissue engineering (BTE) area.
Yunxiang Luo   +14 more
doaj   +1 more source

Conformal folding Dynamics of Amyloid $β$-$τ$ Oligomer in Neuronal Dysfunction [PDF]

open access: yesarXiv, 2023
In this work, we develop model for neuronal degeneration based on polymer chain folding dynamics and their connectivity in various scale. In the first phase, we just developed the model and numerical simulation need to be complete in order to complete the mathematical development of the disease progression.
arxiv  

PoissonSeg: Semi-Supervised Few-Shot Medical Image Segmentation via Poisson Learning [PDF]

open access: yesarXiv, 2021
The application of deep learning to medical image segmentation has been hampered due to the lack of abundant pixel-level annotated data. Few-shot Semantic Segmentation (FSS) is a promising strategy for breaking the deadlock. However, a high-performing FSS model still requires sufficient pixel-level annotated classes for training to avoid overfitting ...
arxiv  

The Degenerating Sex: Female Sterilisation, Medical Authority and Racial Purity in Catholic Brazil [PDF]

open access: yesMedical History, 2020
This article examines female sterilisation practices in early twentieth-century Rio de Janeiro, Brazil. It argues that the medical profession, particularly obstetricians and psychiatrists, used debates over the issue to solidify its moral and political standing during two political moments of Brazilian history: when the Brazilian government separated ...
openaire   +3 more sources

CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling

open access: yesMolecular Cancer, 2019
Background CircMYO10 is a circular RNA generated by back-splicing of gene MYO10 and is upregulated in osteosarcoma cell lines, but its functional role in osteosarcoma is still unknown.
Junxin Chen   +13 more
doaj   +1 more source

Sympathetic activity is correlated with satellite cell aging and myogenesis via β2-adrenoceptor

open access: yesStem Cell Research & Therapy, 2021
Background and objective Sympathetic activity plays an important role in the proliferation and differentiation of stem cells, and it changes over time, thereby exerting differential effects on various stem cell types.
Shiguo Yuan   +6 more
doaj   +1 more source

Generalizable Medical Image Segmentation via Random Amplitude Mixup and Domain-Specific Image Restoration [PDF]

open access: yesarXiv, 2022
For medical image analysis, segmentation models trained on one or several domains lack generalization ability to unseen domains due to discrepancies between different data acquisition policies. We argue that the degeneration in segmentation performance is mainly attributed to overfitting to source domains and domain shift.
arxiv  

Physical disruption of intervertebral disc promotes cell clustering and a degenerative phenotype [PDF]

open access: yes, 2019
© 2019, The Author(s). To test the hypothesis that physical disruption of an intervertebral disc disturbs cell-matrix binding, leading to cell clustering and increased expression of matrix degrading enzymes that contribute towards degenerative disc cell ...
Adams, M.A.   +6 more
core   +1 more source

Choosing the right animal model for osteomyelitis research: Considerations and challenges

open access: yesJournal of Orthopaedic Translation, 2023
Osteomyelitis is a debilitating bone disorder characterized by an inflammatory process involving the bone marrow, bone cortex, periosteum, and surrounding soft tissue, which can ultimately result in bone destruction.
Shen Huang   +4 more
doaj  

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