Automatic detection and counting of retina cell nuclei using deep learning [PDF]
The ability to automatically detect, classify, calculate the size, number, and grade of retinal cells and other biological objects is critically important in eye disease like age-related macular degeneration (AMD). In this paper, we developed an automated tool based on deep learning technique and Mask R-CNN model to analyze large datasets of ...
arxiv +1 more source
IntroductionDecellularized tendon extracellular matrix (tECM) perfectly provides the natural environment and holds great potential for bone regeneration in Bone tissue engineering (BTE) area.
Yunxiang Luo+14 more
doaj +1 more source
Conformal folding Dynamics of Amyloid $β$-$τ$ Oligomer in Neuronal Dysfunction [PDF]
In this work, we develop model for neuronal degeneration based on polymer chain folding dynamics and their connectivity in various scale. In the first phase, we just developed the model and numerical simulation need to be complete in order to complete the mathematical development of the disease progression.
arxiv
PoissonSeg: Semi-Supervised Few-Shot Medical Image Segmentation via Poisson Learning [PDF]
The application of deep learning to medical image segmentation has been hampered due to the lack of abundant pixel-level annotated data. Few-shot Semantic Segmentation (FSS) is a promising strategy for breaking the deadlock. However, a high-performing FSS model still requires sufficient pixel-level annotated classes for training to avoid overfitting ...
arxiv
The Degenerating Sex: Female Sterilisation, Medical Authority and Racial Purity in Catholic Brazil [PDF]
This article examines female sterilisation practices in early twentieth-century Rio de Janeiro, Brazil. It argues that the medical profession, particularly obstetricians and psychiatrists, used debates over the issue to solidify its moral and political standing during two political moments of Brazilian history: when the Brazilian government separated ...
openaire +3 more sources
Background CircMYO10 is a circular RNA generated by back-splicing of gene MYO10 and is upregulated in osteosarcoma cell lines, but its functional role in osteosarcoma is still unknown.
Junxin Chen+13 more
doaj +1 more source
Sympathetic activity is correlated with satellite cell aging and myogenesis via β2-adrenoceptor
Background and objective Sympathetic activity plays an important role in the proliferation and differentiation of stem cells, and it changes over time, thereby exerting differential effects on various stem cell types.
Shiguo Yuan+6 more
doaj +1 more source
Generalizable Medical Image Segmentation via Random Amplitude Mixup and Domain-Specific Image Restoration [PDF]
For medical image analysis, segmentation models trained on one or several domains lack generalization ability to unseen domains due to discrepancies between different data acquisition policies. We argue that the degeneration in segmentation performance is mainly attributed to overfitting to source domains and domain shift.
arxiv
Physical disruption of intervertebral disc promotes cell clustering and a degenerative phenotype [PDF]
© 2019, The Author(s). To test the hypothesis that physical disruption of an intervertebral disc disturbs cell-matrix binding, leading to cell clustering and increased expression of matrix degrading enzymes that contribute towards degenerative disc cell ...
Adams, M.A.+6 more
core +1 more source
Choosing the right animal model for osteomyelitis research: Considerations and challenges
Osteomyelitis is a debilitating bone disorder characterized by an inflammatory process involving the bone marrow, bone cortex, periosteum, and surrounding soft tissue, which can ultimately result in bone destruction.
Shen Huang+4 more
doaj