Results 61 to 70 of about 564,044 (302)

Racial/ethnic differences in neuropsychological test performance in frontotemporal degeneration

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
BACKGROUND Racial and/or ethnic differences in neuropsychological test performance are understudied in frontotemporal degeneration (FTD) but their identification is critical to identifying ways to improve care of representative FTD populations.
Melanie A. Matyi, Emma Rhodes, Sheina Emrani, Hannah A. Jin, David J. Irwin, Corey T. McMillan, Lauren Massimo   +6 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Sympathetic activity is correlated with satellite cell aging and myogenesis via β2-adrenoceptor

Stem Cell Research & Therapy, 2021
Background and objective Sympathetic activity plays an important role in the proliferation and differentiation of stem cells, and it changes over time, thereby exerting differential effects on various stem cell types.
Shiguo Yuan, Sheng Zheng, Kai Zheng, Yanping Gao, Meixiong Chen, Yikai Li, Xiaochun Bai   +6 more
doaj   +1 more source

The Degenerating Sex: Female Sterilisation, Medical Authority and Racial Purity in Catholic Brazil [PDF]

Medical History, 2020
This article examines female sterilisation practices in early twentieth-century Rio de Janeiro, Brazil. It argues that the medical profession, particularly obstetricians and psychiatrists, used debates over the issue to solidify its moral and political standing during two political moments of Brazilian history: when the Brazilian government separated ...
openaire   +3 more sources

Intravitreal Administration of Human Bone Marrow CD34+ Stem Cells in a Murine Model of Retinal Degeneration. [PDF]

, 2016
PurposeIntravitreal murine lineage-negative bone marrow (BM) hematopoietic cells slow down retinal degeneration. Because human BM CD34+ hematopoietic cells are not precisely comparable to murine cells, this study examined the effect of intravitreal human
Annett, Geralyn, Cary, Whitney, Moisseiev, Elad, Motta, Monica, Murphy, Christopher J, Nolta, Jan A, Oltjen, Sharon, Park, Susanna S, Smit-McBride, Zeljka, Zawadzki, Robert J, Zhang, Pengfei   +10 more
core   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Aged skin exacerbates experimental osteoarthritis via enhanced IL-36R signaling

Nature Communications
Age-related inflammation plays a pivotal role in osteoarthritis (OA) pathogenesis, but the mechanism is not fully understood. Here, we identify decreased IL-36 receptor antagonists (IL-36Ra) in epidermal keratinocytes from a premature-aged skin mice ...
Dalin Chen, Chong Wang, Changsheng Yang, Qinwei Cheng, Liangyu Chen, Panpan Yang, Zilin Zou, Zining Wang, Honghao Li, Yun Xiao, Junfeng Wu, Ee Ke, Xiaogang Wang, Bin Huang, Xiaochun Bai, Kai Li   +15 more
doaj   +1 more source

Aneurysmal Degeneration of Medically-Managed Acute Type B Aortic Dissections† [PDF]

Journal of Vascular Surgery, 2014
hypertension (89.9% vs 90.4%, P 1⁄4 .61). OPs were associated with higher mortality rates (1.9% vs 0.6%, P 1⁄4 .0004), postoperative worsening of renal function (1.4% vs 0.4%, P 1⁄4 .002), cardiac events (3.5% vs 1.4%, P < .0001), respiratory complications (3.2% vs 1.1%, P < .0001), and combined outcomes (6.8% vs 2.3%, P < .0001).
Durham, Christopher A., Aranson, Nathan J., Ergul, Emel A., Wang, Linda J., Patel, Virendra I., Cambria, Richard P., Conrad, Mark F.   +6 more
openaire   +1 more source

BMQ [PDF]

, 1964
BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial ...
Barnard, Donna R., Byrne, John J., Carey, Robert J., Chen, Joyce L., Chen, S. C. Andrew, Cohen, Marcia E., Constantine, Herbert, Dearing W. P., Ebaugh, Franklin G., Jr., England, Mary Jan, England, Robert A., Golub, Burton P., Goodman, Max L., Ingelfinger, Franz J., Kaufman, S. A., Keefer, Chester S., Levitan, Ruven, McLellan, Patricia A., Melby, James C., Mitchell, Anita, Moyer, Elizabeth K., Nidorf, Louis, Osler, Leonard D., Scheff, Saul, Seifert, Donald E., Sherry, S. Norman, Taylor, Charles E., Tedeschi, C. G., Walker, Sydnay, III, Weiner, Leonard, Wold, Sylvester M.   +30 more
core  

Rates of lobar atrophy in asymptomatic MAPT mutation carriers. [PDF]

, 2019
IntroductionThe aim of this study was to investigate the rates of lobar atrophy in the asymptomatic microtubule-associated protein tau (MAPT) mutation carriers.MethodsMAPT mutation carriers (n = 14; 10 asymptomatic, 4 converters from ...
Boeve, Bradley F, Boxer, Adam L, Brushaber, Danielle, Chen, Qin, Dheel, Christina, Fields, Julie, Forsberg, Leah, Gavrilova, Ralitza, Gearhart, Debra, Graff-Radford, Jonathan, Graff-Radford, Neill R, Jack, Clifford R, Jones, David T, Kantarci, Kejal, Knopman, David S, Kremers, Walter K, Lapid, Maria, LEFFTDS Consortium, Lesnick, Timothy G, Rademakers, Rosa, Rosen, Howie, Senjem, Matthew, Syrjanen, Jeremy, Tosakulwong, Nirubol, Wszolek, Zbigniew K   +24 more
core   +2 more sources