Results 81 to 90 of about 194,117 (268)

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

open access: yesActa Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs   +12 more
wiley   +1 more source

The Choroid and Optical Coherence Tomography

open access: yesTürk Oftalmoloji Dergisi, 2016
The choroid is the most vascular tissue in the eye and it plays an important role in the pathophysiology of various common chorioretinal diseases such as central serous retinopathy, age-related macular degeneration and degenerative myopia.
Taha Sezer   +2 more
doaj   +1 more source

Genome-wide analysis points to roles for extracellular matrix remodeling, the visual cycle, and neuronal development in myopia [PDF]

open access: yesarXiv, 2012
Myopia, or nearsightedness, is the most common eye disorder, resulting primarily from excess elongation of the eye. The etiology of myopia, although known to be complex, is poorly understood. Here we report the largest ever genome-wide association study (43,360 participants) on myopia in Europeans.
arxiv  

Where the Weather Comes From [PDF]

open access: yes, 2018
When Andreas Malm observed that “not even the weather belongs fully to the moment,” he was looking forward from 2016, considering the cumulative impact of present emissions on “generations not yet born.” The reverse is also true: present storms have ...
Vanek, Morgan
core   +1 more source

Aqueous humour concentrations of HB‐EGF, EGF and VEGF‐A and axial length in humans

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate relationships between the intraocular concentrations of heparin‐binding epidermal growth factor (HB‐EGF), epidermal growth factor (EGF) and vascular endothelial growth factor A (VEGF‐A) in dependence on axial length in humans. Design Clinical interventional cohort study.
Wen‐Da Zhou   +8 more
wiley   +1 more source

Automatic lesion segmentation and Pathological Myopia classification in fundus images [PDF]

open access: yesarXiv, 2020
In this paper we present algorithms to diagnosis Pathological Myopia (PM) and detection of retinal structures and lesions such asOptic Disc (OD), Fovea, Atrophy and Detachment. All these tasks were performed in fundus imaging from PM patients and they are requirements to participate in the Pathologic Myopia Challenge (PALM). The challenge was organized
arxiv  

Myopia prediction for adolescents via time-aware deep learning [PDF]

open access: yesarXiv, 2022
Background: Quantitative prediction of the adolescents' spherical equivalent based on their variable-length historical vision records. Methods: From October 2019 to March 2022, we examined binocular uncorrected visual acuity, axial length, corneal curvature, and axial of 75,172 eyes from 37,586 adolescents aged 6-20 years in Chengdu, China.
arxiv  

Comparative efficacy of intravitreal anti‐VEGF therapy for neovascular age‐related macular degeneration: A systematic review with network meta‐analysis

open access: yesActa Ophthalmologica, EarlyView.
Abstract The aim of this review was to evaluate the comparative efficacy of intravitreal anti‐vascular endothelial growth factor (anti‐VEGF) therapy for neovascular AMD. We searched 12 literature databases for randomised clinical trials (RCT) on anti‐VEGF therapy for neovascular AMD and extracted data on: change from baseline to 12 months in best ...
Emilie T. S. Butler   +17 more
wiley   +1 more source

Morphological changes of sclera in rats with experimental myopia [PDF]

open access: yesМорфологія, 2014
Background. The absence of adequate experimental myopia model is the actual problem in pathophysiological studying of the myopia progression. Studies of the chick eye have formed the basis for several hypotheses of myopic development.
Ulyanova N.A.   +2 more
doaj  

On the moduli space of ricci flat metrics on a K3 surface [PDF]

open access: yesarXiv, 2020
We show that the moduli space of Ricci flat metrics of unit volume (including orbifold metrics) on a K3 surface is simply connected and that it has the same rational cohomology as the automorphism group of the K3 lattice $(-E_8)^{\oplus 2}\oplus U^{\oplus 3}$.
arxiv  

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