Results 41 to 50 of about 4,421 (195)

Incidental Colonic Pneumatosis Intestinalis With Pneumoperitoneum Managed Conservatively. [PDF]

Clin Case Rep
ABSTRACT Pneumoperitoneum accompanying pneumatosis intestinalis can mimic intestinal perforation but does not always require surgery. In asymptomatic, hemodynamically stable patients without high‐risk CT features, conservative management with careful observation and medication review may help avoid unnecessary laparotomy.
Omura T, Aritake T.
europepmc   +2 more sources

Insulin degludec overdose in an adolescent with type 1 diabetes: proactive management including monitoring using the Freestyle Libre flash glucose monitoring system

Endocrinology, Diabetes & Metabolism Case Reports, 2018
An adolescent with type 1 diabetes and a history of self-harm, which included intentional overdoses and insulin omission, presented with an insulin degludec overdose.
Harmony Thompson, Helen Lunt, Cate Fleckney, Steven Soule   +3 more
doaj   +1 more source

Improved health status with insulin degludec compared with insulin glargine in people with Type 1 diabetes

Diabet. Med. 29, 716720 (2012) Abstract Aims The efficacy and safety of insulin degludec (degludec), a new-generation ultra-long-acting basal insulin, was compared with insulin glargine (glargine) in people with Type 1 diabetes mellitus in a 16-week ...
Jendle J, Ratner RE, Roberts AP, Meneghini L, Johansen T, Christensen TE, Home PD, Birkeland KI, Wendisch U   +8 more
core   +5 more sources

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić, Christina Antza, Anastasios Poutachidis, Smaro Palaska, Elvira Meni Maria Gkrinia, Andrea Katrin Faour, Yusuf Ziya Sener, Seher Sener, Rehena Sultana   +8 more
wiley   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

National advisory board on diabetes mellitus: unsolved issues and new opportunities for diabetes treatment

Сахарный диабет, 2014
In June 2014, the national experts on diabetes mellitus discussed the opportunities to improve the efficacy and outcomes of diabetes treatment using the strategy of patient-oriented care in diabetes.
Gagik Radikovich Galstyan
doaj   +1 more source

Anti‐obesity medications and incident ocular outcomes: A systematic review and network meta‐analysis

VIEW, EarlyView.
In this systematic review and network meta‑analysis of 140 studies, anti‑obesity medications showed heterogeneous ocular safety profiles. Semaglutide was associated with higher NAION risk (observational data), whereas dual/multi‑agonists and glucagon‐like peptide‐1 receptor agonists demonstrated favourable glaucoma and overall ocular outcomes ...
Linge Jian, Keke Zhang, Wenwen He, Yan Ke, Yi Lu, Xiangjia Zhu   +5 more
wiley   +1 more source

Retrospective trial of long acting analogues detemir and degludec usage in children and adolescents to overcome glucose variability caused by dawn phenomenon and reverse dawn phenomenon

Сахарный диабет, 2021
Backgraund: Children with type 1 diabetes mellitus (T1DM) need more insulin late in the evening (reverse dawn phenomenon (RDP)), and adolescents need more insulin yearly in the morning (dawn phenomenon (DP)); these cause blood glucose variability. Modern
A. V. Vitebskaya, E. V. Shreder, A. V. Popovich, E. A. Pisareva   +3 more
doaj   +1 more source

Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes

British Journal of Pharmacology, EarlyView.
Abstract Incretin‐based therapies have gained momentum as a key strategy for reducing cardiovascular risk in individuals with obesity and/or type 2 diabetes (T2D). It remains unclear whether the cardiovascular benefits reflect a direct reduction in atherogenic lipoproteins—namely, low‐density lipoproteins (LDL), very low‐density lipoproteins (VLDL) and
Andrea Baragetti, Giuseppe Danilo Norata
wiley   +1 more source

Pediatric diabetes: Potential for insulin degludec

Indian Journal of Endocrinology and Metabolism, 2014
Comprehensive guidelines, published recently by the International Society for Pediatric and Adolescent Diabetes (ISPAD) describe the use of insulin in children and adolescents in great detail.[1] These guidelines provide a bird's eye view of the subject, and also clarify micro management issues, which challenge the pediatric diabetes care provider from
Sanjay Kalra, Ambika Gopalakrishnan Unnikrishnan, Rakesh Sahay   +2 more
openaire   +3 more sources