Results 171 to 180 of about 2,374,007 (316)

Optimized atrazine biodegradation in Egyptian soils via native bacterial isolates and molecular insights using different statistical methods. [PDF]

Sci Rep
Shamseldin A, Ibrahim ES, Sabery SA, Gozalan H.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Machine performance degradation assessment and remaining useful life prediction using proportional hazard model and SVM

This paper proposes a three-stage method involved system identification techniques, proportional hazard model, and support vector machine for assessing the machine health degradation and forecasting the machine remaining useful life (RUL).
Tran, Van Tung
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Polyurethane biodegradation by Fusarium parceramosum with insights into kinetic modelling and metabolic pathway. [PDF]

Bioresour Bioprocess
Sahu P, Sherigar A, Raval R, Lin C, Selvaraj S.   +4 more
europepmc   +1 more source

Linear polysulfides : their characterisation and degradation pathways [PDF]

Linear polysulfides (LPs) are widely used in high performance sealants. The typical structure of the polymer is: H(SC2H40CH2OC2H4S)nH. We have completely characterised the complex components that make up commercially used LPs, by means of electrospray
Mahon, Andrea
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Linking Degradation Pathways, Additive Transformation, and Contaminant Profiles in Post-Consumer HDPE: Implications for Recycling Quality. [PDF]

Polymers (Basel)
Kucbel M, Raclavská H, Růžičková J, Šafář M, Švédová B, Slamová K, Kantor P, Braun P.   +7 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Fabrication of novel nitrogen-doped δ-Al₂O₃ NPs: characterization and performance evaluation for electrocatalytic degradation of organic dyes. [PDF]

Nanoscale Adv
Kamoun EA, Mosleh AT, Hossni HA, Yousef TA, Ragab NAM, Zahran HY, Ganesh V, Hafez M, Yahia IS, Fareed SA.   +9 more
europepmc   +1 more source