Results 151 to 160 of about 2,986,953 (305)

Targeted Protein Degradation: From Molecular Mechanisms to Emerging Therapeutic Strategies. [PDF]

MedComm (2020)
Guo H, Duan H, Liu Y, Fang K, Xiao L, Bai L, Qu X, Yan X, Zhang K.   +8 more
europepmc   +1 more source

Study on pre processing and storage conditions for extraction of chlorophyll from altemantherasessilis (L.) and knetics of degradation of chlorophyll

, 2019
Extraction of chlorophyll from various plants is a key topic of scientific and commercial interest Altemantherasessilis was used for theextraction of chlorophyll as a locally available plant in Sri Lanka.
Amarasinghe, BMWPK, Prashantha, MAB, Amarasinghe, ADUS, Jinasena, MAM   +3 more
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Soil amendments reshape alpine meadow microbial communities across degradation gradients by modulating nutrient availability. [PDF]

PLoS One
Wang N, Zhang Z, Zhou H, Wen Y, Wang X, Song H, Du Y.   +6 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Forced Degradation Study of Vonoprazan Fumarate by HPLC and Characterisation of Its Degradation Products Using LC-QTOF-MS/MS. [PDF]

Rapid Commun Mass Spectrom
Bhatt N, Sonaje D, Samanthula G.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Selective Chain Scission of L-Lactide/ε-Caprolactone Chain Shuttled Copolymers. [PDF]

ChemSusChem
Noon A, Fichaux L, Mosca X, Lowy PA, Bousquet T, Pelinski L, Bonnet F, Ramalho JPP, Favrelle-Huret A, Zinck P.   +9 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

The Dual Nature of RNA Ligation and Degradation by T4 RNA Ligase 1: Insights Into an AMP-Driven, Nucleobase-Dependent Reverse Reaction. [PDF]

Chembiochem
Adachi N, Takahagi W, Terazawa S, Abe RF, Masuda N, Fujishima K.   +5 more
europepmc   +1 more source