Results 131 to 140 of about 1,404,700 (259)

Degree-day values [PDF]

Nature, 1979
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

When Heat Meets Pollutants: Integrating Degree-Days and Chemical Activity Concepts for the Assessment of Temperature-Driven Toxicity. [PDF]

Environ Sci Technol
Gorokhova E, Alurralde G, Steigerwald S, Abel S, Saladin Y, Sobek A, Eriksson-Wiklund AK, Garbaras A.   +7 more
europepmc   +1 more source

Generic calibration of a simple model of diurnal temperature variations for spatial analysis of accumulated degree-days. [PDF]

Int J Biometeorol, 2018
Felber R, Stoeckli S, Calanca P.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Predicting the Onset Date of Cucumber Powdery Mildew Based on Growing Degree Days and Leaf Wetness Duration in Greenhouse Environment. [PDF]

Plant Pathol J
Son M, Jeong H, Jung JY, Park J, Park J, Park H, Yoon J, Jung SH, Sim CB, Kim KH, Park SY.   +10 more
europepmc   +1 more source

Variability of growing degree days in Poland in response to ongoing climate changes in Europe. [PDF]

Int J Biometeorol, 2017
Wypych A, Sulikowska A, Ustrnul Z, Czekierda D.   +3 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Exploring Fasciola infection dynamics in Coastal Caspian Sea region: implications of growing degree days (GDD) and Malone index across varied climatic zones in Iran. [PDF]

Parasitol Res
Meshgi B, Modabbernia G, Meshgi K.
europepmc   +1 more source

U.S. Agro-Climate in 20^th Century: Growing Degree Days, First and Last Frost, Growing Season Length, and Impacts on Crop Yields. [PDF]

Sci Rep, 2018
Kukal MS, Irmak S.
europepmc   +1 more source