Results 111 to 120 of about 1,409,799 (295)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2008 Another week of slightly cool days with scattered storms has Iowa farmers facing uneven stands in many fields. Cumulative heat during the week of June 23 lagged behind long term averages by 10 to 25 degree days in Iowa.
Pope, Richard
core
Watermelon response to plastic mulch and row covers
European Journal of Horticultural Science, 2006 L. Ibarra-Jiménez +4 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
CCSM3 NA Climates 22ka-0ka, Growing Degree Days
, 2016 Downscaled and debiased paleoclimatic simulations from CCSM3 (Liu et al. 2009). Downscaled to 0.5deg lat/lon and decadal resolution for North America for 22,000 years ago to 20th century.
John W. Williams (101516) +9 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Degree Days and Building Energy Demand [PDF]
, 2015 Degree-days (DD) are a climatic indicator that can be used in the assessment and analysis of weather related to energy consumption of buildings. Essentially, degree-days are a summation of the differences between the outdoor temperature and some ...
Lo Brano, V. +5 more
core
Assessment of Regional Residential Energy Performance Using Degree Days
BuildingsThis study proposes a climate-adjusted framework for evaluating regional residential energy performance by introducing Energy Consumption per Degree-Day (ECDD), an indicator that normalizes end-use energy consumption by climatic demand.
Akio Tanaka +2 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Cover crop mixture expression is influenced by nitrogen availability and growing degree days. [PDF]
PLoS One, 2020 Baraibar B +6 more
europepmc +1 more source