Results 61 to 70 of about 1,409,799 (295)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Predicting the Phenology of Herbivorous Insects

Ecology and Evolution
Models of herbivorous insect phenology can be used to make agriculture more sustainable and to better manage the effects of climate change on natural communities. The phenology of herbivorous insects depends on heat time, but exactly how it varies across
Zimo Yang, Elise Woodruff, David Held, Nate B. Hardy   +3 more
doaj   +1 more source

Multi-Objective Optimization of Design nZEBs in Uzbekistan

Proceedings of the International Conference on Applied Innovations in IT
The growth in energy demand from the residential sector in Uzbekistan points to the urgency to adopt nearly zero-energy building (nZEB) strategies that can be tailored to domestic climate and economic conditions.
Sayyora Asanova, Azamat Shukurov, Akbar Halimov, Jasurjon Akhatov   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Forecasting Day-Ahead Electricity Demand in Australia Using a CNN-LSTM Model with an Attention Mechanism

Applied Sciences
Accurate energy demand forecasting is vital for optimizing resource allocation and energy efficiency. Despite advancements in various prediction models, existing approaches often struggle to capture the complex, nonlinear relationships between ...
Laial Alsmadi, Gang Lei, Li Li
doaj   +1 more source

Threshold temperature constraints on reproduction of the banded killifish (Fundulus diaphanus)

Journal of Freshwater Ecology, 2019
Banded killifish (Fundulus diaphanus) are a small, freshwater fish that have a wide distribution in eastern North America and are considered a species-at-risk on the island of Newfoundland.
H. D. Penney, M. A. Litt, C. F. Purchase
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Growing Degree Days (GDD)

, 1977
This publication provides a map of Growing Degree Days (GDD) for South Dakota and explains how GDD is calculated.
Derscheid, Lyle A., Lytle, William F.
core   +1 more source

The Effects of Temperature on the Development and Survival of Bathycoelia distincta (Hemiptera: Pentatomidae), a Significant Pest of Macadamia in South Africa

Insects
Temperature is the most influential condition affecting insect development and population dynamics. Understanding its impact and other important factors, such as diet, could provide fine-scale predictions of species abundance and distribution in space ...
Mulalo M. Muluvhahothe, Elsje Joubert, Stefan H. Foord   +2 more
doaj   +1 more source