Results 81 to 90 of about 1,409,799 (295)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

PREDICTING THE EMERGENCE OF CORN ROOTWORM (Diabrotica virgifera virgifera LeConte) IN ESTERN SLAVONIA [PDF]

open access: yesPoljoprivreda, 2009
Corn (Zea mays L.) is one of the most important field crops in Croatia, country as well as in the world. It is subjected to many pests, among which is corn rootworm.
Dražen Đoić
doaj  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Utilizing Growing Degree Days for Corn Production

open access: yes, 2019
This fact sheet explains the concepts and formulas in determining growing degree ...
Israelsen, Clark   +2 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Monthly average of heating and cooling degree days

open access: yes, 2017
Data show the average of heating and cooling degree days in the eu28 at nuts2 ...
Chiara Scaramuzzino, Pietro Zambelli
core   +1 more source

Phenological Development, Thermal Requirement, and Quality of ‘BRS Núbia’ (Vitis vinifera L. x Vitis labrusca L.) Grapes on Different Rootstocks

open access: yesHorticulturae
The cultivation of table grapes in Brazil is economically significant, with production influenced by edaphoclimatic factors and rootstock selection. The cultivar ‘BRS Núbia’ (Vitis vinifera L. x Vitis labrusca L.) is a promising alternative; however, its
Harleson Sidney Almeida Monteiro   +9 more
doaj   +1 more source

Spatial-Temporal Changes and Associated Determinants of Global Heating Degree Days. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Li Y, Li J, Xu A, Feng Z, Hu C, Zhao G.
europepmc   +1 more source

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