Results 91 to 100 of about 1,293,710 (359)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The evaluation of the order of approximation of the matrix method for numerical integration of the boundary value problems for systems of linear non-homogeneous ordinary differential equations of the second order with variable coefficients. Message 1. Boundary value problems with boundary conditions of the first kind

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2016
We present the first message of the cycle from two articles where the rearrangement of the order of approximation of the matrix method of numerical integration depending on the degree in the Taylor’s polynomial expansion of solutions of boundary value ...
Vladimir N Maklakov
doaj   +1 more source

Trace Finite Element Methods for Surface Vector-Laplace Equations

, 2019
In this paper we analyze a class of trace finite element methods (TraceFEM) for the discretization of vector-Laplace equations. A key issue in the finite element discretization of such problems is the treatment of the constraint that the unknown vector ...
Jankuhn, Thomas, Reusken, Arnold
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

On the degree of approximation by Gauss Weierstrass integrals

International Journal of Mathematics and Mathematical Sciences, 2000
We obtain the degree of approximation of functions belonging to class Lip(ψ(u,v);p),   p>1 using the Gauss Weierstrass integral of the double Fourier series of f(x,y).
Huzoor H. Khan, Govind Ram
doaj   +1 more source

Trigonometric generated Lp degree of approximation

Annals of Communications in Mathematics, 2023
In this article we continue the study of smooth Picard singular integral operators that started in [3], see there chapters 10-14. This time the foundation of our research is a trigonometric Taylor’s formula. We establish the Lp convergence of our operators to the unit operator with rates via Jackson type inequalities engaging the first Lp modulus of ...
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Sur la suite des opérateurs Bernstein composés (On the sequence of composite Bernstein operators)

Journal of Numerical Analysis and Approximation Theory, 2013
We consider a sequence of composite Bernstein operators and the quadrature formulae associated with them. Upper bounds for the approximation error of continuous functions and for the approximation of integrals of continuous functions are given.
H. Gonska, I. Raşa
doaj   +2 more sources