Results 81 to 90 of about 166,471,289 (242)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Sur la suite des opérateurs Bernstein composés (On the sequence of composite Bernstein operators)

Journal of Numerical Analysis and Approximation Theory, 2013
We consider a sequence of composite Bernstein operators and the quadrature formulae associated with them. Upper bounds for the approximation error of continuous functions and for the approximation of integrals of continuous functions are given.
H. Gonska, I. Raşa
doaj   +2 more sources

Degree of Monotone Approximation in , p Lα Spaces

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
The aim of this paper is to study the best approximation of unbounded functions in the weighted spaces , 1, 0 , p p L α α ≥>.
I. Z. Shamkhi, S. K. Jassim
doaj  

Numerical integration by the matrix method of boundary value problems for linear inhomogeneous ordinary differential equations of the third order with variable coefficients

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2018
The use of the Taylor polynomial of the second degree when approximating the derivatives by finite differences leads to the second order of approximation of the traditional method of nets in the numerical integration of second-order ordinary differential
Vladimir N Maklakov, Yanina G Stelmakh
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

On the approximation of integrable functions by some special matrix means of Fourier series

Demonstratio Mathematica, 2017
The results concerninig pointwise approximation and product of summability methods corresponding to the theorems of Xh. Z. Krasniqi [Poincare J. Anal. Appl., 2014, 1, 1-8] and W. Łenski and B. Szal [Math. Slovaca, 2016, 66(6), 1-12] are generalized. Some
Kranz Radosława, Rzepka Aleksandra
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

On the Complexity of Optimization over the Standard Simplex [PDF]

We review complexity results for minimizing polynomials over the standard simplex and unit hypercube.In addition, we show that there exists a polynomial time approximation scheme (PTAS) for minimizing Lipschitz continuous functions and functions with ...
Klerk, E. de, Hertog, D. den, Elfadul, G.E.E.   +2 more
core  

A study on degree of approximation by Karamata summability method

Journal of Inequalities and Applications, 2011
Vuĉkoviĉ [Maths. Zeitchr. 89, 192 (1965)] and Kathal [Riv. Math. Univ. Parma, Italy 10, 33-38 (1969)] have studied summability of Fourier series by Karamata (K λ ) summability method.
Nigam Hare, Sharma Kusum
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source