Results 91 to 100 of about 166,471,289 (242)

Numerical Approach for the Frequency-Weighted Hankel-Norm Approximation [PDF]

, 2001
We derive new projection formulas for the model reduction method based on the frequency-weighted Hankel norm approximation (FWHNA). These formulas extend the applicability of the FWHNA method to frequency weights expressed as antistable right/left ...
Varga, Andras
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The best uniform quadratic approximation of circular arcs with high accuracy

Open Mathematics, 2016
In this article, the issue of the best uniform approximation of circular arcs with parametrically defined polynomial curves is considered. The best uniform approximation of degree 2 to a circular arc is given in explicit form.
Rababah Abedallah
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

On the degree of approximation by modified Szasz operator

Journal of Numerical Analysis and Approximation Theory, 1988
Not available.
S. M. Mazhar
doaj   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Hardness of approximation for orthogonal rectangle packing and covering problems [PDF]

, 2009
Bansal and Sviridenko [N. Bansal, M. Sviridenko, New approximability and inapproximability results for 2-dimensional bin packing, in: Proceedings of the 15th Annual ACM–SIAM Symposium on Discrete Algorithms, SODA, 2004, pp.
Chlebikova, Janka, Chlebík, Miroslav, Chlebik, M., Miroslav Chlebik (4461319), Janka Chlebíková (16060964)   +4 more
core   +1 more source

The second order modulus revisited: remarks, applications, problems

Journal of Numerical Analysis and Approximation Theory
Several questions concerning the second order modulus of smoothness are addressed in this note. The central part is a refined analysis of a construction of certain smooth functions by Zhuk and its application to several problems in approximation theory,
Heiner Gonska, Ralitza K. Kovacheva
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source