Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Effect of polymerization mode on shrinkage kinetics and degree of conversion of dual-curing bulk-fill resin composites. [PDF]
Burrer P +7 more
europepmc +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
The influence of salivary contamination during light curing on degree of conversion and color stability of two composite resins. [PDF]
Rohaninasab M +4 more
europepmc +1 more source
Novel 1,2-Bismethacrylate-3-Eugenyl Propane for Resin Composites: Synthesis, Characterization, Rheological, and Degree of Conversion. [PDF]
Al-Kahtani HM +6 more
europepmc +1 more source
Effect of Infiltrating a Commercial Etch-and-Rinse Bonding Agent with Bioactive Nanoparticles on the Degree of Conversion of Adhesive and Flexural Strength of Dentin [PDF]
Elham Alipour +2 more
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Dual role of piperine: Preserving the degree of conversion of resin cement on bleached enamel and exhibiting antimicrobial activity. [PDF]
de Flaviano Albuquerque TE +9 more
europepmc +1 more source

