Results 191 to 200 of about 407,418 (293)

Three-Dimensional Printed Resin: Impact of Different Cleaning Protocols on Degree of Conversion and Tensile Bond Strength to a Composite Resin Using Various Adhesive Systems. [PDF]

Materials (Basel), 2023
Lankes V, Reymus M, Mayinger F, Coldea A, Liebermann A, Hoffmann M, Stawarczyk B.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Effects of post-curing conditions on degree of conversion, microhardness, and stainability of 3D printed permanent resins. [PDF]

BMC Oral Health
Aktug Karademir S, Atasoy S, Akarsu S, Karaaslan E.   +3 more
europepmc   +1 more source

The Effect of Femtosecond Laser Irradiation and Plasmon Field on the Degree of Conversion of a UDMA-TEGDMA Copolymer Nanocomposite Doped with Gold Nanorods. [PDF]

Int J Mol Sci, 2022
Bonyár A, Szalóki M, Borók A, Rigó I, Kámán J, Zangana S, Veres M, Rácz P, Aladi M, Kedves MÁ, Szokol Á, Petrik P, Fogarassy Z, Molnár K, Csete M, Szenes A, Tóth E, Vas D, Papp I, Galbács G, Csernai LP, Biró TS, Kroó N, Collaboration N.   +23 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Evaluation of the degree of conversion of flowable bulk fill and dual-cure composite resins for intracanal root reinforcement in teeth with structurally weakened roots: An <i>in vitro</i> Fourier transformer infrared study. [PDF]

J Conserv Dent Endod
Bhandari SS, Margasahayam SV, Shenoy VU, Patil AB, Surwade MA.   +4 more
europepmc   +1 more source

Raman Spectroscopy as Spectral Tool for Assessing the Degree of Conversion after Curing of Two Resin-Based Materials Used in Restorative Dentistry. [PDF]

Diagnostics (Basel), 2022
Gatin E, Iordache SM, Matei E, Luculescu CR, Iordache AM, Grigorescu CEA, Ilici RR.   +6 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Effect of preheating and curing lamp distance on the degree of conversion of four nanohybrid resins: An in vitro study. [PDF]

J Clin Exp Dent
Uribe-Hernández L, Latorre-Correa F, Perea-Lowery L, Ardila CM.   +3 more
europepmc   +1 more source

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source