Results 171 to 180 of about 1,559,848 (287)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Properties of Composite Resins Early After Curing: Color Stability, Degree of Conversion, and Dimensional Stability. [PDF]

Int J Dent
Amirinejad S, Panahandeh N, Torabzadeh H.   +2 more
europepmc   +1 more source

Degree of conversion and microhardness of resin cements photoactivated through glass ceramic. [PDF]

J Clin Exp Dent, 2021
Pereira CB, Magalhães CS, Lages FS, Ferreira RC, da Silva EH, da Silveira RR, Corrêa EC, Fantini CL, Moreira AN.   +8 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Degree of Conversion and Microshear Bond Strength of New Composite to Postcured Composite Resin Surface Treated With Ethyl Acetate. [PDF]

Int J Dent
Rostamzadeh T, Tavangar SM, Golsorkhtabar F.   +2 more
europepmc   +1 more source

Effects of Translucency and Thickness of Lithium Disilicate-Reinforced Glass-Ceramic Veneers on the Degree of Conversion of a Purely Light-Curing Bonding Resin: An In Vitro Study. [PDF]

Polymers (Basel), 2023
Poca A, De Peretti Della Rocca K, Nasr K, Ducassé R, Canceill T.   +4 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Effect of light guide tip diameter on the degree of conversion and depth of cure of bulk-fill composites. [PDF]

Eur Oral Res
Keles ZH, Tarim B.
europepmc   +1 more source

Comparative Evaluation of Bulk-Fill Composite Resins: Knoop Microhardness, Diametral Tensile Strength and Degree of Conversion. [PDF]

Clin Cosmet Investig Dent, 2022
Strini BS, Marques JFL, Pereira R, Sobral-Souza DF, Pecorari VGA, Liporoni PCS, Aguiar FHB.   +6 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source