Results 31 to 40 of about 2,264,079 (275)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Design and Analysis of Three-Degree-of-Freedom High-stiffness Robot
Jixie chuandong, 2021 Combining robot technology and CNC machining technology， a three -degree-of-freedom high-stiffness robot is designed. The three-degree-of-freedom structure is determined by the analysis of processing requirements， and the theoretical analysis of the ...
Meijia Zhi +4 more
doaj
Phase Transition in Perovskite Manganites with Orbital Degree of Freedom
, 1999 Roles of orbital degree of freedom of Mn ions in phase transition as a function of temperature and hole concentration in perovskite manganites are studied. It is shown that the orbital order-disorder transition is of the first order in the wide region of
A. J. Millis +45 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Applicability of the free field Sustained Auditory Attention Ability Test (SAAAT)
International Archives of Otorhinolaryngology, 2012 Introduction: The attention is an underlying neuropsychology function to all the cognitive processes. The auditory deficiency compromises the normal development of the child, modifying diverse auditory abilities, including the attention ...
Mariza Ribeiro Feniman +3 more
doaj +1 more source
Dynamic Response Analysis of Structures Using Legendre–Galerkin Matrix Method
Applied Sciences, 2021 The solution of the motion equation for a structural system under prescribed loading and the prediction of the induced accelerations, velocities, and displacements is of special importance in structural engineering applications.
Mohammad Momeni +6 more
doaj +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Polarization and wavelength routers based on diffractive neural network
Frontiers of OptoelectronicsIn the field of information processing, all-optical routers are significant for achieving high-speed, high-capacity signal processing and transmission.
Xiaohong Lin +5 more
doaj +1 more source
Depinning of domain walls with an internal degree of freedom
, 2009 Taking into account the coupling between the position of the wall and an internal degree of freedom, namely its phase $\phi$, we examine, in the rigid wall approximation, the dynamics of a magnetic domain wall subject to a weak pinning potential.
Barnes, Stewart E. +3 more
core +2 more sources
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source