Results 101 to 110 of about 175,923,861 (334)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

A Numerical–Experimental Approach for Multi‐Matrix Fiber‐Reinforced Plastics Characterization Using Finite Element Model Updating

Advanced Engineering Materials, EarlyView.
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora, Tales V. Lisbôa, Axel Spickenheuer, Rogério J. Marczak, Jakson M. Vassoler   +4 more
wiley   +1 more source

A Simplified Laminar Flow Model for the Pultrusion of Glass Fiber/Polyethylene Terephthalate Commingled Yarns

Advanced Engineering Materials, EarlyView.
A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares, Nadège Bouchonneau, Christian Jochum, Donald Radford   +3 more
wiley   +1 more source

Emulsion Polymerization of Water-soluble Monomers [PDF]

, 1955
The rate and the degree of polymerization are measured and compared in the mass- and emulsion- polymerization of styrene, methyl methacrylate, methyl acrylate, vinyl caproate and vinyl acetate in the presence of soap molecule.
MOTOYAMA, Takuhiko, OKAMURA, Seizo
core  

Modification Methods’ Effects on the Characteristics of Carboxylated Cellulose Fibers: Carboxyl Group Introduction Method versus Physical Properties

BioResources
Cotton fibers were modified by TEMPO oxidation, sodium periodate oxidation, and sodium chloroacetate etherification to obtain carboxylated cellulose fibers with similar carboxyl content (about 70 mmol/100 g). The characteristics of carboxylated cellulose
Jian Wang, Yubo Wang, Zetan Liu, Xinyi Shao, Yuxuan Lin, Wenbao Song, Dehua Xu, Yifei Gao, Jialan Han   +8 more
doaj   +2 more sources

Kinetic‐Directed Thermodynamic Repair Enables the Synthesis of High‐Strain 2D Sub‐Stoichiometric COFs

Advanced Science
Two‐dimensional covalent organic frameworks (2D COFs) are promising photocatalysts due to their tunable electronic structures and ordered π‐stacking. Sub‐stoichiometric COFs, featuring periodically unreacted functional groups, offer enhanced property ...
Xiang Pei, Kaifu Yu, Pan He, Hongqing Wu, Bo Jiang, Kewen Shu, Yang Li, Ya Tang, Lijian Ma   +8 more
doaj   +1 more source

Flexural Behavior of 3D‐Printed Porous Bouligand‐Structured Polymers: Influence of Pitch Angle and Porosity

Advanced Engineering Materials, EarlyView.
This study examines how helicoidal architectures with different porosities respond to bending. Adjusting layer angle and spacing in 3D‐printed polymers reveals clear tradeoffs between stiffness, strength, and energy absorption. Experiments and simulations highlight designs that distribute stress effectively, offering pathways for optimizing lightweight
Praveenkumar Subhash Patil, Edward D. McCarthy, Parvez Alam   +2 more
wiley   +1 more source

Polymerization-Induced Self-Assembly (PISA) Using ICAR ATRP at Low Catalyst Concentration

, 2016
Polymerization-induced self-assembly (PISA) was achieved by conducting an initiators for continuous activator regeneration atom transfer radical polymerization (ICAR ATRP) at low ppm of copper catalyst concentration. A poly­(oligo­(ethylene oxide) methyl
Guowei Wang (1715704), Sipei Li (2070901), Guojun Xie (1783813), Krzysztof Matyjaszewski (1247034), Michael Schmitt (17761), Jiajun Yan (489314), Michael R. Bockstaller (1707220), Bongjoon Lee (1747012), Xiangcheng Pan (1460371), Zongyu Wang (1460374), Liye Fu (3333909)   +10 more
core   +1 more source

Degree of conversion and microhardness of different composite resins polymerized with an advanced LED-curing unit

BMC Oral Health
Background The aim was to evaluate the effects of different curing times (3s/10s/20s) of an advanced Light-Emitting Diode (LED) curing unit on the degree of conversion (DC%), microhardness, and hardness ratio of three different composite resin materials.
Gozde Ozciftci, Hayal Boyacioglu, Lezize Sebnem Turkun   +2 more
doaj   +1 more source

Comparison of Triply Periodic Minimal Surface Energy Absorbers Under Uniaxial Compressive Loading

Advanced Engineering Materials, EarlyView.
This study investigates LCD 3D printed Triply Periodic Minimal Surface (TPMS) structures as mechanical energy absorbers. By comparing various base designs and layered combinations under uniaxial compression, it identifies that a Diamond‐Gyroid sandwich structure offers superior performance.
Sergej Grednev, Noah‐Lean Roschlaub, Anne Jung   +2 more
wiley   +1 more source