Results 31 to 40 of about 104,176 (263)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Molecules, 2021 Euterpe oleracea Mart. (Arecaceae) is an endogenous palm tree from the Amazon region. Its seeds correspond to 85% of the fruit’s weight, a primary solid residue generated from pulp production, the accumulation of which represents a potential source of ...
Gabriel Rocha Martins +9 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Effect of cavity depth on degree of conversion and microhardness of low-shrinkage resin composites
BMC Oral HealthBackground The study aimed to investigate the effect of different cavity depths on the degree of conversion (DC) and surface microhardness (MH) of low-shrinkage resin composites.
Seda Gömleksiz, Oğuzhan Gömleksiz
doaj +1 more source
Dentistry 3000Objective: To evaluate and compered the effect of different temperatures (5°C, 37°C and room temp. ±23°C) pre- cured and post-cured for three universal- Chroma composite materials (Hybrid-Nano fillers, Supra-Nano, Nano filler) on the polymerization ...
Fanar Turki Al-Jadwaa +2 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Czech Journal of Animal Science, 2005 Research was conducted to determine the physiological effect of substituting 5% of maize starch with cellulose, inulin and oligofructose in the diet of rats.
J. Juśkiewicz +2 more
doaj +1 more source
Polymerization shrinkage kinetics and degree of conversion of resin composites
Journal of Oral Science, 2020 This study compared shrinkage strain, polymerization shrinkage kinetics, and degree of conversion (DC) of a set of resin composites and investigated their influencing factors. Ten commercial resin composites were assessed, and 5 specimens (n = 5) were developed for material and subjected to light curing using light emitting diode light at 650 mW/cm2 ...
Tong, Xu +6 more
openaire +3 more sources
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source