Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Measuring factor substitution and technological change in the Tunisian agricultural sector, 1971 - 2000 [PDF]
The production structure of Tunisian agriculture over the last three decades is investigated using a translog variable cost function. Standard results of neoclassical duality theory are used to obtain measures of elasticities of substitution between ...
Chebil, Ali +2 more
core
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Measuring the possibilities of interfuel substitution [PDF]
What are the costs of making consumption of production activities use less-polluting fuels? The author reviews how the fuel mix used by different industries has changed over time and examines 2 techniques for estimating the responsiveness of fuel demand ...
Bacon, Robert
core
High-Performance Acetylated Ioncell-F Fibers with Low Degree of Substitution. [PDF]
ACS Sustain Chem Eng, 2018 Asaadi S +5 more
europepmc +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Choice of the substitution currency in Russia: How to explain the dollar's dominance? [PDF]
The analysis of external economic relations of Russia reveals a paradox: while Europe is the main trade and direct investment partner of Russia, this is far from being the case concerning its currency’s role in Russia's financial activities.
Dorbec, Anna
core
Multiple-Use Microplate Assay for Submicromolar Ultra High-Throughput Separation of Amines Based on their Degree of Substitution. [PDF]
ChemistryOpenVezse P, Tóth T, Huszthy P, Golcs Á.
europepmc +1 more source
Characterization of Type-II Acetylated Cellulose Nanocrystals with Various Degree of Substitution and Its Compatibility in PLA Films. [PDF]
Polymers (Basel), 2017 Dong F, Yan M, Jin C, Li S.
europepmc +1 more source