Results 81 to 90 of about 1,089,730 (251)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nucleotide diversity and linkage disequilibrium in 11 expressed resistance candidate genes in Lolium perenne

BMC Plant Biology, 2007
Background Association analysis is an alternative way for QTL mapping in ryegrass. So far, knowledge on nucleotide diversity and linkage disequilibrium in ryegrass is lacking, which is essential for the efficiency of association analyses.
Asp Torben, Schejbel Britt, Frei Uschi, Xing Yongzhong, Lübberstedt Thomas   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Bringing circuit theory into spatial occupancy models to assess landscape connectivity

Methods in Ecology and Evolution
Occupancy models were originally developed to better understand species distribution while accounting for imperfect detection. Because species distribution is not only shaped by habitat quality but also by the ability of individuals to reach suitable ...
Maëlis Kervellec, Thibaut Couturier, Sarah Bauduin, Delphine Chenesseau, Pierre Defos du Rau, Nolwenn Drouet‐Hoguet, Christophe Duchamp, Julien Steinmetz, Jean‐Michel Vandel, Olivier Gimenez   +9 more
doaj   +1 more source

Invasion of a Virulent Phytophthora infestans Genotype at the Landscape Level; Does Spatial Heterogeneity Matter? [PDF]

Proper landscape-scale deployment of disease resistant genotypes of agricultural crop species could make those crops less vulnerable to invasion by resistance breaking genotypes.
Kessel, G.J.T., Rossing, W.A.H., Skelsey, P., Werf, W., van der   +3 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Simple random walk on distance-regular graphs [PDF]

, 2013
A survey is presented of known results concerning simple random walk on the class of distance-regular graphs. One of the highlights is that electric resistance and hitting times between points can be explicitly calculated and given strong bounds for ...
Markowsky, Greg
core  

On-Site Wireless Power Generation

, 2018
Conventional wireless power transfer systems consist of a microwave power generator and a microwave power receiver separated by some distance. To realize efficient power transfer, the system is typically brought to resonance, and the coupled-antenna mode
Alu, A., Chowkwale, B., Liu, F., Ra'di, Y., Simovski, C. R., Tretyakov, S. A., Valagiannopoulos, C. A.   +6 more
core   +1 more source