Results 111 to 120 of about 9,193,291 (353)

Functional conservation of sequence determinants at rapidly evolving regulatory regions across mammals. [PDF]

open access: yesPLoS Computational Biology, 2018
Recent advances in epigenomics have made it possible to map genome-wide regulatory regions using empirical methods. Subsequent comparative epigenomic studies have revealed that regulatory regions diverge rapidly between genome of different species, and ...
Iksoo Huh   +3 more
doaj   +1 more source

Degree sequence of the generalized Sierpiński ‎graph

open access: yesContributions to Discrete Mathematics, 2020
Sierpiński graphs are studied in fractal theory and have applications in diverse areas including dynamic systems, chemistry, psychology, probability, and computer science. Polymer networks and WK-recursive networks can be modeled by generalized Sierpiński graphs.
Mahsa Khatibi   +2 more
openaire   +3 more sources

Asymptotic Enumeration by Degree Sequence of Graphs of High Degree [PDF]

open access: yesEuropean Journal of Combinatorics, 1990
We consider the estimation of the number of labelled simple graphs with degree sequence d1, d2, . . . , dn by using an n-dimensional Cauchy integral. For sufficiently small ε and any c > 2/3, an asymptotic formula is obtained when |di − d| < n1/2 + ε for all i and d = d(ni) satisfies min{d, n − d − 1) ⩾ cn/log n as n→ ∞.
Brendan D. McKay, Nicholas C. Wormald
openaire   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Geometric randomization of real networks with prescribed degree sequence

open access: yesNew Journal of Physics, 2019
We introduce a model for the randomization of complex networks with geometric structure. The geometric randomization (GR) model assumes a homogeneous distribution of the nodes in a hidden similarity space and uses rewirings of the links to find ...
Michele Starnini   +2 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

A permutation method for network assembly.

open access: yesPLoS ONE, 2020
We present a method for assembling directed networks given a prescribed bi-degree (in- and out-degree) sequence. This method utilises permutations of initial adjacency matrix assemblies that conform to the prescribed in-degree sequence, yet violate the ...
Shawn A Means   +2 more
doaj   +1 more source

Different forms of metric characterizations of classes of Banach spaces [PDF]

open access: yes, 2011
For each sequence X of finite-dimensional Banach spaces there exists a sequence H of finite connected nweighted graphs with maximum degree 3 such that the following conditions on a Banach space Y are equivalent: (1) Y admits uniformly isomorphic ...
Ostrovskii, Mikhail I.
core  

Modifying a Graph's Degree Sequence and the Testablity of Degree Sequence Properties

open access: yes, 2020
We show that if the degree sequence of a graph $G$ is close in $\ell_1$-distance to a given realizable degree sequence $(d_1,\dots,d_n)$, then $G$ is close in edit distance to a graph with degree sequence $(d_1,\dots,d_n)$. We then use this result to prove that every graph property defined in terms of the degree sequence is testable in the dense graph ...
openaire   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

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