Results 121 to 130 of about 5,011,430 (289)

On triangular biregular degree sequences

open access: yesDiscrete Mathematics
11 pages, 1 ...
Benjamin Egan, Yuri Nikolayevsky
openaire   +4 more sources

On Representing the Degree Sequences of Sublogarithmic-Degree Wheeler Graphs

open access: yes, 2022
We show how to store a searchable partial-sums data structure with constant query time for a static sequence $S$ of $n$ positive integers in $o \left( \frac{\log n}{(\log \log n)^2} \right)$, in $n H_k (S) + o (n)$ bits for $k \in o \left( \frac{\log n}{(\log \log n)^2} \right)$. It follows that if a Wheeler graph on $n$ vertices has maximum degree in $
openaire   +3 more sources

Hadwiger's conjecture for degree sequences

open access: yesJournal of Combinatorial Theory, Series B, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Guantao Chen, Katsuhiro Ota
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Limit of trees with fixed degree sequence

open access: yes, 2021
We use a new stick-breaking construction, also introduced independently by Addario-Berry, Donderwinkel, Maazoun, and Martin in arXiv:2107.09726, to study uniform rooted trees with fixed degree sequence D (D-trees).
Blanc-Renaudie, Arthur
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Majorization and the degree sequence of trees

open access: yesIberoamerican Journal of Science Measurement and Communication
Objective. This study investigated the relation between the degree sequences of trees and the majorization order. Design/Methodology/Approach. The majorization technique was employed in accordance with the tenets of Muirhead’s theorem. Results. In this study, we proved a theorem that provides a necessary and sufficient condition for degree sequences of
Leo Egghe, Ronald Rousseau
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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