Results 121 to 130 of about 5,011,430 (289)
On triangular biregular degree sequences
11 pages, 1 ...
Benjamin Egan, Yuri Nikolayevsky
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On Representing the Degree Sequences of Sublogarithmic-Degree Wheeler Graphs
We show how to store a searchable partial-sums data structure with constant query time for a static sequence $S$ of $n$ positive integers in $o \left( \frac{\log n}{(\log \log n)^2} \right)$, in $n H_k (S) + o (n)$ bits for $k \in o \left( \frac{\log n}{(\log \log n)^2} \right)$. It follows that if a Wheeler graph on $n$ vertices has maximum degree in $
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Hadwiger's conjecture for degree sequences
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Guantao Chen, Katsuhiro Ota
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Limit of trees with fixed degree sequence
We use a new stick-breaking construction, also introduced independently by Addario-Berry, Donderwinkel, Maazoun, and Martin in arXiv:2107.09726, to study uniform rooted trees with fixed degree sequence D (D-trees).
Blanc-Renaudie, Arthur
core
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
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Majorization and the degree sequence of trees
Objective. This study investigated the relation between the degree sequences of trees and the majorization order. Design/Methodology/Approach. The majorization technique was employed in accordance with the tenets of Muirhead’s theorem. Results. In this study, we proved a theorem that provides a necessary and sufficient condition for degree sequences of
Leo Egghe, Ronald Rousseau
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Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

