Results 121 to 130 of about 971,776 (299)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
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On relationship between reformulated Sombor and other vertex--degree indices [PDF]
Transactions on CombinatoricsLet $G=(V,E)$, $V=\{v_1, v_2,\ldots,v_n\}$, $E=\{e_1, e_2,\ldots,e_m\}$, be a simple connected graph with $n\ge 2$ vertices and $m$ edges, with vertex degree sequence $\Delta=d_1\ge d_2\ge \cdots \ge d_n=\delta$, $ d_i=d(v_i)$, and edge degree sequence $\
Emina Milovanovic +4 more
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Rao's degree sequence conjecture
Journal of Combinatorial Theory, Series B, 2014 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Maria Chudnovsky, Paul D. Seymour
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
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Extremal trees with fixed degree sequence for $\sigma$-irregularity [PDF]
Discrete Mathematics Letters, 2023 Darko Dimitrov +3 more
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A Review Study of Prime Period Perfect Gaussian Integer Sequences
AxiomsPrime period sequences can serve as the fundamental tool to construct arbitrary composite period sequences. This is a review study of the prime period perfect Gaussian integer sequence (PGIS).
Ho-Hsuan Chang +3 more
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Complexity Estimation of Infrared Image Sequence for Automatic Target Track
Xibei Gongye Daxue Xuebao, 2019 Infrared image complexity metrics are an important task of automatic target recognition and track performance assessment. Traditional metrics, such as statistical variance and signal-to-noise ratio, targeted to single frame infrared image. However, there
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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