Results 131 to 140 of about 9,193,291 (353)
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
On neighbourhood degree sequences of complex networks [PDF]
AbstractNetwork topology is a fundamental aspect of network science that allows us to gather insights into the complicated relational architectures of the world we inhabit. We provide a first specific study of neighbourhood degree sequences in complex networks.
openaire +7 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Extremal trees with fixed degree sequence for atom-bond connectivity index
The atom-bond connectivity (ABC) index of a graph G is the sum of √ d(u)+d(v)−2 d(u)d(v) over all edges uv ofG, whered(u) is the degree of vertexuinG. We characterize the extremal trees withfixed degree sequence that maximize and minimize the ABC index ...
Rundan Xing, Bo Zhou
semanticscholar +1 more source
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source
On relationship between reformulated Sombor and other vertex--degree indices [PDF]
Let $G=(V,E)$, $V=\{v_1, v_2,\ldots,v_n\}$, $E=\{e_1, e_2,\ldots,e_m\}$, be a simple connected graph with $n\ge 2$ vertices and $m$ edges, with vertex degree sequence $\Delta=d_1\ge d_2\ge \cdots \ge d_n=\delta$, $ d_i=d(v_i)$, and edge degree sequence $\
Emina Milovanovic+4 more
doaj +1 more source
Note on the degree of convergence of sequences of polynomials [PDF]
J. L. Walsh, E. N. Nilson
openalex +1 more source
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever+1 more
wiley +1 more source
Extremal trees with fixed degree sequence for $\sigma$-irregularity [PDF]
Darko Dimitrov+3 more
doaj +1 more source
A Review Study of Prime Period Perfect Gaussian Integer Sequences
Prime period sequences can serve as the fundamental tool to construct arbitrary composite period sequences. This is a review study of the prime period perfect Gaussian integer sequence (PGIS).
Ho-Hsuan Chang+3 more
doaj +1 more source