Results 61 to 70 of about 1,107 (189)
Cancer Cell International, 2021 Background Morphine, a µ-opioid receptor (MOR) agonist, has been shown to be related to the activity of cancer cells, and a higher morphine dosage reduces the survival time of patients with lung cancer.
Xingyun Liu +6 more
doaj +1 more source
Guidance on the use of read‐across for chemical safety assessment in food and feed
EFSA Journal, Volume 23, Issue 7, July 2025.Abstract Read‐across is a method used in chemical risk assessment to predict the toxicological properties of a target substance by using data from structurally and mechanistically similar substances, known as source substances. EFSA's Scientific Committee has developed an approach for using read‐across in food and feed risk assessment.
EFSA Scientific Committee +26 more
wiley +1 more source
Efficacy and mechanism of action of Deguelin in suppressing metastasis of 4T1 cells [PDF]
Clinical & Experimental Metastasis, 2013 Cancer related deaths in breast cancer patients are due to metastasis of the disease. Murine 4T1 cells (Murine mammary cancer cell line developed from 6-thioguanine resistant tumor) provide an excellent research tool for metastasis related studies because these cells are highly aggressive and readily metastasize to the lungs.
Rajeshwari R, Mehta +10 more
openaire +2 more sources
Journal of Nanotechnology, Volume 2025, Issue 1, 2025.The current investigation focuses on the photocatalytic degradation and biological applications of M. sericea leaf extract‐mediated Ag3PO4/SnO2 nanocomposites (NCs). The synthesized nanomaterials were characterized through various characterization techniques to determine their structural and optical properties.
Vrushali Manoj Hadkar +3 more
wiley +1 more source
Deguelin inhibits human hepatocellular carcinoma by antiangiogenesis and apoptosis
Oncology Reports, 2008 Deguelin is a rotenoid isolated from several plant species, which has been reported to have chemopreventive effects in skin, mammary, colon and lung cancers. The effects of deguelin on the proliferation and apoptosis of hepatic cancer cells were assessed by MTT assay and flow cytometric analysis.
Ju-Hee, Lee +5 more
openaire +3 more sources
Health Science Reports, Volume 7, Issue 12, December 2024.ABSTRACT Background and Aims The biological function of lysosomes has been increasingly appreciated in cancer. However, the relationship between lysosome and lung adenocarcinoma (LUAD) was not well understood. In this study, a lysosome‐related signature was developed for LUAD risk stratification and prognosis prediction.
Wei Ye +4 more
wiley +1 more source
Brown Stink Bug Mortality by Seed Extracts of Tephrosia Vogelii Containing Deguelin and Tephrosin
Brazilian Archives of Biology and Technology, 2018 Extracts of the seeds of Tephrosia vogelii Hook. f. were studied in relation to its chemical composition and toxicity to the brown stink bug Euschistus heros (F.).
Adriana Yatie Mikami +2 more
doaj +1 more source
Effect of Deguelin on the growth and expression of signaling molecules in TNBC cells.
, 2013 A. Effect of deguelin on MDA-MB 231 cells in the presence of EGF (1 ng or 20 ng) alone, Deguelin alone (31–500 nM)or Deguelin+EGF. The cells were plated in six well plates, allowed to attach overnight, then treated with indicated test compound/(s) (in ...
Harshadadevi Katta (419863) +7 more
core +1 more source
Food Science &Nutrition, Volume 12, Issue 5, Page 3025-3045, May 2024.Polyphenols, such as kaempferol, catechins, apigenin, chlorogenic acid, rosmarinic acid, and caffeic acid, have shown their ability to serve as potential antidiabetic medicines. Also, the use of polyphenols might have a few side effects although relatively less than available medications. Abstract In the middle of an ever‐changing landscape of diabetes
Dipa Aryal +11 more
wiley +1 more source
Chemistry &Biodiversity, Volume 21, Issue 4, April 2024.Abstract This perspective delves into the investigation of synthetic and naturally occurring inhibitors, their patterns of inhibition, and the effectiveness of newly utilized natural compounds as inhibitors targeting the Ornithine decarboxylase enzyme. This enzyme is known to target the MYC oncogene, thereby establishing a connection between polyamine ...
Preeti Nanda Sahu, Anik Sen
wiley +1 more source