Results 91 to 100 of about 1,107 (189)
Cytotoxic effects of deguelin in cultured HNSCC cells.
Hep-2 cells were exposed to deguelin at a various concentration (10, 25, 50, 100 and 200 µM) for 72 hours (A) or exposed to 100 µM of deguelin for different time points (12, 24, 48 and 72 hours) (B), cell viability was then measured by MTT assay.
Chun-cheng Lu (276392) +6 more
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Deguelin affects EGFR/c-Met and their downstream target molecules such as p-STAT3, p-ERK, p-AKT, c-Myc and Survivin and there by affect growth/survival of breast cancer cells.
Harshadadevi Katta (419863) +7 more
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Since the first report about cytoplasmic nucleophosmin (NPM) in acute myelogenous leukemia with a normal karyotype was announced, the shuttling activity of NPM and its proper subcellular localization have drawn many attentions.
Wu, Q, Shu, W, Cui, G, Chen, Y, Li, R
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Total Synthesis of dl-Deguelin
FUKAMI, Hiroshi +3 more
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Supplementary Table 1 from A Novel Derivative of the Natural Agent Deguelin for Cancer Chemoprevention and ...
Gordon Mills (499661) +13 more
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Deguelin induces cellular ceramide synthesis.
Hep-2 cells were exposed to 100 µM of deguelin with or without fumonisin B1 (20 µM) for indicated time points, intracellular ceramide level was analyzed using methods mentioned above (A). Hep-2 cells were treated with fumonisin B1 (20 µM) or C6-ceramide (
Chun-cheng Lu (276392) +6 more
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Concise Synthesis of the Chemopreventitive Agent (±)-Deguelin via a Key 6-Endo Hydroarylation
A concise total synthesis of (±)-deguelin was achieved with a longest linear sequence of six steps in 68% yield.
Dalibor Sames (1432975) +1 more
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Deguelin gavage is well tolerated.
Bodyweight is determined before and after Deguelin treatment. The gain in bodyweight is a sign for good tolerance of the substance. The graph represents the increases in bodyweight vs. weight at begin of the experiment.
Bertram Scheller (318724) +8 more
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Correction: A Novel Derivative of Deguelin [PDF]
openaire +1 more source
OBJECTIVE: To investigate antitumor activity and molecular mechanism of deguelin to the human U937 leukaemia cells and to explore the mechanisms regulating cell cycle and nucleoporin 98 (Nup98) and nucleoporin 88 (Nup88) in vitro. METHODS: The effects of
Chen, WH +5 more
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