Results 151 to 160 of about 1,019 (188)
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Deguelin and Its Role in Chronic Diseases
2016Deguelin is one of four major naturally occurring rotenoids isolated from root extracts and is best recognized as a NADH: ubiquinone oxidoreductase (complex I) inhibitor, resulting in significant alterations in mitochondrial function. Deguelin has also been implicated as a regulator of apoptosis through signaling pathways, such as the (PI3K)/Akt ...
Jonathan, Boyd, Alice, Han
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Regulatory effects of deguelin on proliferation and cell cycle of Raji cells
Journal of Huazhong University of Science and Technology [Medical Sciences], 2013The underlying mechanism of deguelin regulating the cell cycle in human Burkitt's lymphoma cell line Raji cells in vitro, and the cytotoxicity of deguelin to Raji cells and human peripheral blood monocular cells (PBMCs) were investigated. The effects of deguelin on the growth of Raji cells were studied by 3-(4, 5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H ...
Jin-Rong, Xiong, Hong-Li, Liu
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Agricultural and Biological Chemistry, 1961
Starting with resorcinol, the total synthesis of dl-deguelin (VI) was accomplished. In the course of this investigation, dihydrodeguelic acid (II), dihydroisodeguelic acid (X), dihydro-dehydrodeguelin (III), dehydrodeguelin (IV), dl-deguelol (V) and dihydro-β-rotenonone (XI) were prepared.
Hiroshi Fukami +3 more
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Starting with resorcinol, the total synthesis of dl-deguelin (VI) was accomplished. In the course of this investigation, dihydrodeguelic acid (II), dihydroisodeguelic acid (X), dihydro-dehydrodeguelin (III), dehydrodeguelin (IV), dl-deguelol (V) and dihydro-β-rotenonone (XI) were prepared.
Hiroshi Fukami +3 more
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Agricultural and Biological Chemistry, 1974
Hiroyoshi Omokawa, Kyohei Yamashita
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Hiroyoshi Omokawa, Kyohei Yamashita
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Effect of deguelin on expression of nup98 in K562 cells
2010The study was purposed to investigate the effect of deguelin on expression of nucleoporin 98 (nup98) in leukemia K562 cells. MTT assay was used to assess the effects of deguelin on cell proliferation. FCM and RT-PCR were used to analyze the changes of nup98 mRNA and protein in K562 cells after treating with deguelin.
He, J, Chen, WH, Chen, Y, Wu, QL
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Degueline: A Rotenoid Constituent ofChadsia grevei
Planta Medica, 1994F, Manjary +6 more
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Crystalline Solvates of Inactive Deguelin
Journal of the American Chemical Society, 1939Lyle D. Goodhue, H. L. Haller
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DEGUELIN. IV. THE STRUCTURE OF DEGUELIN AND TEPHROSIN
Journal of the American Chemical Society, 1932openaire +1 more source
DEGUELIN. II. RELATIONSHIPS BETWEEN DEGUELIN AND ROTENONE
Journal of the American Chemical Society, 1931openaire +1 more source