Results 91 to 100 of about 1,195 (187)
Deguelin downregulates AKT/NFκB mediated prosurvival signals in CLL cells.
, 2016 (A) PBMCs from 3 CLL patients were treated for 24h with 0, 10, or 100 μM deguelin. Viability was evaluated by flow cytometry after Annexin V/IP staining. Figure shows immunoreactive bands for several deguelin target molecules and β-actin in western blots
Silvia Rosado (39145) +9 more
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PLoS ONE, 2015 Plants with pesticidal properties have been investigated for decades as alternatives to synthetics, but most progress has been shown in the laboratory. Consequently, research on pesticidal plants is failing to address gaps in our knowledge that constrain
Prisila Mkenda +5 more
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Viruses, 2019 Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that establishes a lifelong persistence in the host through both chronic and latent states of infection [...]
Beatrice Mercorelli +4 more
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, 2016 Deguelin exhibits potent apoptotic and antiangiogenic activities in a variety of transformed cells and cancer cells. Deguelin also exhibits potent tumor suppressive effects in xenograft tumor models for many human cancers.
Ji-Hyeon Park (554738) +21 more
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, 2018 Deguelin, a rotenoid, is isolated from a natural plant species, and has biological activities including antitumor function. In the present study, we investigated the effect of deguelin on the cell adhesion, migration and invasion of NCI-H292 human lung ...
Jaw-Chyun Chen +8 more
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Deguelin blocks cells survival signal pathways and induces apoptosis of HL-60 cells in vitro
, 2009 To investigate the anti-cancer effects and molecular mechanism of deguelin on the human leukemia HL-60 cells, to explore the expression and clinical significance of p-AKT, survivin and Bcl-2 in leukemia cell line HL-60 cell. Cell growth rate was assessed
Wu, Q +4 more
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, 2013 Deguelin affects EGFR/c-Met and their downstream target molecules such as p-STAT3, p-ERK, p-AKT, c-Myc and Survivin and there by affect growth/survival of breast cancer cells.
Harshadadevi Katta (419863) +7 more
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Cytotoxic effects of deguelin in cultured HNSCC cells.
, 2013 Hep-2 cells were exposed to deguelin at a various concentration (10, 25, 50, 100 and 200 µM) for 72 hours (A) or exposed to 100 µM of deguelin for different time points (12, 24, 48 and 72 hours) (B), cell viability was then measured by MTT assay.
Chun-cheng Lu (276392) +6 more
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, 2012 [[abstract]]It has been shown that deguelin, one of the compounds of rotenoids from flavonoid family, induced cytotoxic effects through induction of cell cycle arrest and apoptosis in many types of human cancer cell lines, but deguelin-affected DNA ...
鍾景光;Chung, Jing-Gung
core
, 2008 Since the first report about cytoplasmic nucleophosmin (NPM) in acute myelogenous leukemia with a normal karyotype was announced, the shuttling activity of NPM and its proper subcellular localization have drawn many attentions.
Wu, Q, Shu, W, Cui, G, Chen, Y, Li, R
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