Results 41 to 50 of about 602,095 (309)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Dehydration regulates structural reorganization of dynamic hydrogels

Nature Communications
The dehydration process is widely recognized as a significant phenomenon in nature. Hydrogels, which are important functional materials with high water content and crosslinked networks, encounter the issue of dehydration in their practical applications ...
Dan Xu, Xintong Meng, Siyuan Liu, Jade Poisson, Philipp Vana, Kai Zhang   +5 more
doaj   +1 more source

Physical and mechanical properties of raspberries subjected to osmotic dehydration and further dehydration by air- and freeze-drying [PDF]

, 2016
The aim of this study was to analyze the effect of the application of dry and wet sucrose infusions, as pretreatments previous to air- and freeze-drying, on mechanical and physical properties of raspberries: water sorption, glass transition temperature ...
Salvatori, Daniela Marisol, Schebor, Carolina Claudia, Sette, Paula Andrea   +2 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

MANUFACTURE OF FOOD PRODUCTS ENRICHED BY FRUITS AND NUTS

Вестник Северо-Кавказского федерального университета, 2022
Intense pace of life in modern conditions dictate the necessity ofpresence on the market offood products directly ready to eat. Suggest ways of improving the technology of snack products you need together with the biologically valuable nutritious product,
Valentin Shipulin, Gennady Kasyanov, Liliya Zotova   +2 more
doaj  

The Onset of In-Vivo Dehydration in Gas -Based Intraperitoneal Hyperthermia and Its Cytotoxic Effects on Colon Cancer Cells

Frontiers in Oncology, 2022
BackgroundPeritoneal metastasis (PM) is an ongoing challenge in surgical oncology. Current therapeutic options, including intravenous and intraperitoneal (i.p.) chemotherapies display limited clinical efficacy, resulting in an overall poor prognosis in ...
Agata Diakun, Tanja Khosrawipour, Tanja Khosrawipour, Agata Mikolajczyk-Martinez, Jakub Nicpoń, Zdzisław Kiełbowicz, Przemysław Prządka, Bartłomiej Liszka, Wojciech Kielan, Kacper Zielinski, Pawel Migdal, Hien Lau, Shiri Li, Veria Khosrawipour, Veria Khosrawipour   +14 more
doaj   +1 more source

PENGARUH PEMBERIAN MINUMAN ISOTONIK TERHADAP MEMORI PADA KEADAAN DEHIDRASI [PDF]

, 2015
Background: Sport is one of popular activities throughout the world. One of the biggest problems found among athletes in sports is dehydration, which causes many bad health issues for athletes themselves.
Adyaksa, Gana, Prasetya, Ari, Purwoko, Yosef   +2 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Assessment of Exercise-Induced Dehydration Status Based on Oral Mucosal Moisture in a Field Survey

Dentistry Journal
Background/Objective: Conventional techniques for evaluating hydration status include the analysis of blood, urine, and body weight. Recently, advancements in dentistry have introduced capacitance sensor-based oral epithelial moisture meters as promising
Gen Tanabe, Tetsuya Hasunuma, Yasuo Takeuchi, Hiroshi Churei, Kairi Hayashi, Kaito Togawa, Naoki Moriya, Toshiaki Ueno   +7 more
doaj   +1 more source

Management of Listeria monocytogenes on Surfaces via Relative Air Humidity: Key Role of Cell Envelope

Foods, 2021
Although relative air humidity (RH) strongly influences microbial survival, its use for fighting surface pathogens in the food industry has been inadequately considered.
Fiona Zoz, Stéphane Guyot, Cosette Grandvalet, Mélanie Ragon, Eric Lesniewska, Sébastien Dupont, Olivier Firmesse, Brigitte Carpentier, Laurent Beney   +8 more
doaj   +1 more source